Literature DB >> 2982646

Adenosine uptake in pyrimidine 5'-nucleotidase deficient human erythrocytes via a high affinity transport system.

T Kagimoto, S Tomino, K Takatsuki.   

Abstract

Using a pulse-labeling technique, 14C-adenosine uptake into pyrimidine 5'-nucleotidase (P5N) deficient erythrocytes (RBC) was found to be impaired. The Lineweaver-Burk plot showed Km values of 2.0 X 10(-3) mM and 0.2 X 10(-3) mM for normal RBC and P5N deficient RBC, respectively. These results indicate that P5N is one of regulators of the adenosine transport system and/or is associated with adenosine carrier protein.

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Year:  1985        PMID： 2982646     DOI： 10.1007/bf02004508

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  24 in total

1.  A possible association between the nucleoside transport system of human erythrocytes and adenosine deaminase.

Authors:  R P Agarwal; R E Parks
Journal:  Biochem Pharmacol       Date:  1975-02-15       Impact factor: 5.858

2.  Transport of a nonphosphorylated nucleoside, 5'-deoxyadenosine, by murine leukemia L1210 cells.

Authors:  D Kessel
Journal:  J Biol Chem       Date:  1978-01-25       Impact factor: 5.157

3.  Characteristics of a pyrimidine-specific 5'-nucleotidase in human erythrocytes.

Authors:  D E Paglia; W N Valentine
Journal:  J Biol Chem       Date:  1975-10-25       Impact factor: 5.157

4.  Inhibition of nucleoside incorporation into HeLa cells by streptovaricin.

Authors:  K B Tan; B R McAuslan
Journal:  Biochem Biophys Res Commun       Date:  1971-01-22       Impact factor: 3.575

5.  Uptake and metabolism of adenosine by human erythrocyte ghosts.

Authors:  J Schrader; R M Berne; R Rubio
Journal:  Am J Physiol       Date:  1972-07

6.  Uptake of adenosine in human erythrocytes.

Authors:  M Kraupp; P Chiba; M M Müller
Journal:  Adv Exp Med Biol       Date:  1979       Impact factor: 2.622

7.  Adenosine transport and metabolism in mouse leukemia cells and in canine thymocytes and peripheral blood leukocytes.

Authors:  C T Lum; R Marz; P G Plagemann; R M Wohlhueter
Journal:  J Cell Physiol       Date:  1979-11       Impact factor: 6.384

8.  Two cases of hereditary hemolytic anemia with pyrimidine 5'-nucleotidase deficiency.

Authors:  S Miwa; Y Ishida; A Kibe; S Uekihara; S Kishimoto
Journal:  Nihon Ketsueki Gakkai Zasshi       Date:  1981-02

9.  Erythrocyte pyrimidine 5'-nucleotidase.

Authors:  J D Torrance; D Whittaker; T Jenkins
Journal:  Br J Haematol       Date:  1980-08       Impact factor: 6.998

10.  Stimulation of uridine uptake in 3T3 cells in associated with increased ATP affinity of uridine-phosphorylating system.

Authors:  G J Goldenberg; W D Stein
Journal:  Nature       Date:  1978-08-03       Impact factor: 49.962
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