Literature DB >> 2982113

Attempts to implicate viruses in myasthenia gravis.

T Aoki, D B Drachman, D M Asher, C J Gibbs, S Bahmanyar, J S Wolinsky.   

Abstract

We investigated the hypothesis that a persistent viral infection of the thymus gland might trigger the autoimmune disease myasthenia gravis (MG). Thymus glands of nine patients with recent onset of MG were studied by a variety of techniques to detect the presence of occult viruses. No evidence of viral infection was found.

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Year:  1985        PMID: 2982113     DOI: 10.1212/wnl.35.2.185

Source DB:  PubMed          Journal:  Neurology        ISSN: 0028-3878            Impact factor:   9.910


  3 in total

Review 1.  Myasthenia gravis: an autoimmune response against the acetylcholine receptor.

Authors:  Y M Graus; M H De Baets
Journal:  Immunol Res       Date:  1993       Impact factor: 2.829

2.  Molecular mimicry and myasthenia gravis. An autoantigenic site of the acetylcholine receptor alpha-subunit that has biologic activity and reacts immunochemically with herpes simplex virus.

Authors:  P L Schwimmbeck; T Dyrberg; D B Drachman; M B Oldstone
Journal:  J Clin Invest       Date:  1989-10       Impact factor: 14.808

3.  Myasthenia gravis-like syndrome induced by expression of interferon gamma in the neuromuscular junction.

Authors:  D Gu; L Wogensen; N A Calcutt; C Xia; S Zhu; J P Merlie; H S Fox; J Lindstrom; H C Powell; N Sarvetnick
Journal:  J Exp Med       Date:  1995-02-01       Impact factor: 14.307

  3 in total

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