Literature DB >> 2981686

Sequential ADP-ribosylation pattern of nucleosomal histones. ADP-ribosylation of nucleosomal histones.

A Huletsky, C Niedergang, A Fréchette, R Aubin, A Gaudreau, G G Poirier.   

Abstract

The pattern of nucleosomal histones poly(ADP-ribosyl)ation is changed under conditions which affect the poly(ADP-ribosyl)ation state of the enzyme. At low NAD concentrations the enzyme can poly(ADP-ribosyl)ate histones H1 and H1, H2A, A2A, and H2B. However at NAD concentrations above 10 microM the enzyme preferentially poly(ADP-ribosyl)ates histone H1 to a hyper ADP-ribosylated form. Furthermore we have observed hyper ADP-ribosylation of histone H2B at NAD concentrations of 10 microM suggesting that histone H2B can undergo the same type of ADP-ribosylation pattern as histone H1. Also at higher NAD concentrations an elongation of the polymer attached to the enzyme and other nuclear proteins takes place.

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Year:  1985        PMID： 2981686     DOI： 10.1111/j.1432-1033.1985.tb08650.x

Source DB:  PubMed          Journal:  Eur J Biochem        ISSN： 0014-2956


  13 in total

Review 1.  Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions.

Authors:  D D'Amours; S Desnoyers; I D'Silva; G G Poirier
Journal:  Biochem J       Date:  1999-09-01       Impact factor: 3.857

2.  ADP-ribosylation in isolated nuclei of Physarum polycephalum.

Authors:  G Golderer; R Schneider; B Auer; P Loidl; P Gröbner
Journal:  Biochem J       Date:  1988-08-01       Impact factor: 3.857

Review 3.  Molecular and biochemical features of poly (ADP-ribose) metabolism.

Authors:  D Lautier; J Lagueux; J Thibodeau; L Ménard; G G Poirier
Journal:  Mol Cell Biochem       Date:  1993-05-26       Impact factor: 3.396

Review 4.  Regulatory mechanisms of poly(ADP-ribose) polymerase.

Authors:  R Alvarez-Gonzalez; T A Watkins; P K Gill; J L Reed; H Mendoza-Alvarez
Journal:  Mol Cell Biochem       Date:  1999-03       Impact factor: 3.396

5.  Cytoplasmic poly(ADP-ribose) polymerase and poly(ADP-ribose) glycohydrolase in AEV-transformed chicken erythroblasts.

Authors:  H Thomassin; C Martins de Sa; K Scherrer; C Maniez; P Mandel
Journal:  Mol Biol Rep       Date:  1988       Impact factor: 2.316

6.  Poly(ADP-ribose) may signal changing metabolic conditions to the chromatin of mammalian cells.

Authors:  P Loetscher; R Alvarez-Gonzalez; F R Althaus
Journal:  Proc Natl Acad Sci U S A       Date:  1987-03       Impact factor: 11.205

Review 7.  Enzymology of ADP-ribose polymer synthesis.

Authors:  R Alvarez-Gonzalez; G Pacheco-Rodriguez; H Mendoza-Alvarez
Journal:  Mol Cell Biochem       Date:  1994-09       Impact factor: 3.396

8.  The nucleosomal surface is the main target of histone ADP-ribosylation in response to DNA damage.

Authors:  Kelly R Karch; Marie-France Langelier; John M Pascal; Benjamin A Garcia
Journal:  Mol Biosyst       Date:  2017-11-21

9.  At least 60 ADP-ribosylated variant histones are present in nuclei from dimethylsulfate-treated and untreated cells.

Authors:  T Boulikas
Journal:  EMBO J       Date:  1988-01       Impact factor: 11.598

Review 10.  The expanding universe of PARP1-mediated molecular and therapeutic mechanisms.

Authors:  Dan Huang; W Lee Kraus
Journal:  Mol Cell       Date:  2022-03-09       Impact factor: 19.328
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