Literature DB >> 2981263

Hemagglutination assay of polypeptide coded by the pre-S region of hepatitis B virus DNA with monoclonal antibody: correlation of pre-S polypeptide with the receptor for polymerized human serum albumin in serums containing hepatitis B antigens.

H Okamoto, M Imai, S Usuda, E Tanaka, K Tachibana, S Mishiro, A Machida, T Nakamura, Y Miyakawa, M Mayumi.   

Abstract

The receptor for polymerized human as well as chimpanzee serum albumins has been identified on the 55-amino acid polypeptide coded by the pre-S region of hepatitis B virus DNA. Monoclonal antibodies were raised against a synthetic polypeptide of 19 amino acid residues representing a hydrophilic region of the pre-S amino acid sequence deduced from hepatitis B virus DNA. Sheep erythrocytes fixed with glutaraldehyde were coated with monoclonal antibody against the synthetic polypeptide to develop a hemagglutination assay for pre-S polypeptide. The pre-S polypeptide was detected in the serum containing hepatitis B surface antigen particles along with hepatitis B e antigen, with titers in parallel with those of the receptor for polymerized human serum albumin.

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Year:  1985        PMID： 2981263

Source DB:  PubMed          Journal:  J Immunol        ISSN： 0022-1767            Impact factor:   5.422


  16 in total

1.  Hepatitis B virus genotyping by enzyme-linked immunosorbent assay in Taiwan.

Authors:  Shu-Fen Liu; Meng-Hsuan Hsieh; Nai-Jen Hou; Ming-Yen Hsieh; Jee-Fu Huang; Chia-Yen Dai; Ming-Lung Yu; Wan-Long Chuang
Journal:  Hepatol Int       Date:  2010-08-03       Impact factor: 6.047

2.  Expression of hepatitis B virus large envelope polypeptide inhibits hepatitis B surface antigen secretion in transgenic mice.

Authors:  F V Chisari; P Filippi; A McLachlan; D R Milich; M Riggs; S Lee; R D Palmiter; C A Pinkert; R L Brinster
Journal:  J Virol       Date:  1986-12       Impact factor: 5.103

3.  Expression of hepatitis B virus surface and core antigens: influences of pre-S and precore sequences.

Authors:  A McLachlan; D R Milich; A K Raney; M G Riggs; J L Hughes; J Sorge; F V Chisari
Journal:  J Virol       Date:  1987-03       Impact factor: 5.103

4.  Changes of pre-S1 and pre-S2 antigens in sera of patients with hepatitis B virus infection.

Authors:  Y Iwasaki; K Matsuura; T Tsuji
Journal:  Gastroenterol Jpn       Date:  1990-08

5.  Failure to detect polyalbumin-binding sites on the woodchuck hepatitis virus surface antigen: implications for the pathogenesis of hepatitis B virus in humans.

Authors:  C J Pohl; P J Cote; R H Purcell; J L Gerin
Journal:  J Virol       Date:  1986-12       Impact factor: 5.103

6.  Hybrid hepatitis B virus core-pre-S proteins synthesized in avirulent Salmonella typhimurium and Salmonella typhi for oral vaccination.

Authors:  F Schödel; S M Kelly; D L Peterson; D R Milich; R Curtiss
Journal:  Infect Immun       Date:  1994-05       Impact factor: 3.441

7.  The position of heterologous epitopes inserted in hepatitis B virus core particles determines their immunogenicity.

Authors:  F Schödel; A M Moriarty; D L Peterson; J A Zheng; J L Hughes; H Will; D J Leturcq; J S McGee; D R Milich
Journal:  J Virol       Date:  1992-01       Impact factor: 5.103

8.  Extracellular production of human hepatitis B virus preS2 antigen as hybrid proteins with Bacillus subtilis alpha-amylases in high-salt-concentration media.

Authors:  K Honda; H Fujieda; K Ogawa; M Imai; H Yamamoto; T Ikeda; K Yamane
Journal:  Appl Microbiol Biotechnol       Date:  1993-11       Impact factor: 4.813

9.  A synthetic peptide vaccine involving the product of the pre-S(2) region of hepatitis B virus DNA: protective efficacy in chimpanzees.

Authors:  Y Itoh; E Takai; H Ohnuma; K Kitajima; F Tsuda; A Machida; S Mishiro; T Nakamura; Y Miyakawa; M Mayumi
Journal:  Proc Natl Acad Sci U S A       Date:  1986-12       Impact factor: 11.205

10.  Electron microscopic study of hepatitis B virus-associated antigens on the infected liver cell membrane in relation to analysis of immune target antigens in chronic hepatitis B.

Authors:  T Saito; T Kamimura; M Ishibashi; H Shinzawa; T Takahashi
Journal:  Gastroenterol Jpn       Date:  1992-12
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