| Literature DB >> 2981053 |
Abstract
It has been shown that myosin molecules attached to Covaspheres can "walk along" polar actin filament in vitro. The driving force for this movement seems to explain only about 1% of the isometric tension developed by a muscle fibre. Therefore, the driving force for the bead movement seems to be incompatible with that found in muscle, and the bead movement cannot be considered as a model for muscle contraction. The origin of the bead movement may be related to a "molecular jet" process, resulting from the rapid ejection of the MgATP splitting products. This "molecular jet" might also explain the movements of many cellular organelles.Entities:
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Year: 1988 PMID: 2981053 DOI: 10.1016/s0022-5193(88)80192-9
Source DB: PubMed Journal: J Theor Biol ISSN: 0022-5193 Impact factor: 2.691