Literature DB >> 2981053

Muscle contraction and movement of cellular organelles: are there two different types of mechanisms for their generation?

J E Morel1, N Bachouchi.   

Abstract

It has been shown that myosin molecules attached to Covaspheres can "walk along" polar actin filament in vitro. The driving force for this movement seems to explain only about 1% of the isometric tension developed by a muscle fibre. Therefore, the driving force for the bead movement seems to be incompatible with that found in muscle, and the bead movement cannot be considered as a model for muscle contraction. The origin of the bead movement may be related to a "molecular jet" process, resulting from the rapid ejection of the MgATP splitting products. This "molecular jet" might also explain the movements of many cellular organelles.

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Year:  1988        PMID: 2981053     DOI: 10.1016/s0022-5193(88)80192-9

Source DB:  PubMed          Journal:  J Theor Biol        ISSN: 0022-5193            Impact factor:   2.691


  1 in total

1.  Isometric tension exerted by a myofibril of the frog at 0 degree C: geometrical considerations.

Authors:  Z Merah; J E Morel
Journal:  J Muscle Res Cell Motil       Date:  1993-12       Impact factor: 2.698

  1 in total

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