Literature DB >> 29809215

Development of glycosynthases with broad glycan specificity for the efficient glyco-remodeling of antibodies.

Sachin S Shivatare1, Lin-Ya Huang, Yi-Fang Zeng, Jung-Yu Liao, Tsai-Hong You, Shi-Yun Wang, Ting Cheng, Chih-Wei Chiu, Ping Chao, Li-Tzu Chen, Tsung-I Tsai, Chiu-Chen Huang, Chung-Yi Wu, Nan-Horng Lin, Chi-Huey Wong.   

Abstract

The first systematic investigation of the effect of high mannose, hybrid, and bi- and tri-antennary complex type glycans on the effector functions of antibodies was achieved by the discovery of novel Endo-S2 mutants generated by site-directed mutagenesis as glycosynthases with broad substrate specificity.

Entities:  

Mesh:

Substances:

Year:  2018        PMID: 29809215     DOI: 10.1039/c8cc03384f

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  11 in total

Review 1.  Structural insights into the mechanisms and specificities of IgG-active endoglycosidases.

Authors:  Jonathan J Du; Erik H Klontz; Marcelo E Guerin; Beatriz Trastoy; Eric J Sundberg
Journal:  Glycobiology       Date:  2020-03-20       Impact factor: 4.313

Review 2.  Oligosaccharide Synthesis and Translational Innovation.

Authors:  Larissa Krasnova; Chi-Huey Wong
Journal:  J Am Chem Soc       Date:  2019-02-18       Impact factor: 15.419

Review 3.  Glycoengineering of Antibodies for Modulating Functions.

Authors:  Lai-Xi Wang; Xin Tong; Chao Li; John P Giddens; Tiezheng Li
Journal:  Annu Rev Biochem       Date:  2019-03-27       Impact factor: 23.643

Review 4.  Sculpting therapeutic monoclonal antibody N-glycans using endoglycosidases.

Authors:  Beatriz Trastoy; Jonathan J Du; Mikel García-Alija; Chao Li; Erik H Klontz; Lai-Xi Wang; Eric J Sundberg; Marcelo E Guerin
Journal:  Curr Opin Struct Biol       Date:  2022-01-05       Impact factor: 6.809

Review 5.  Chemoenzymatic Methods for the Synthesis of Glycoproteins.

Authors:  Chao Li; Lai-Xi Wang
Journal:  Chem Rev       Date:  2018-08-24       Impact factor: 60.622

Review 6.  Recent Progress in Chemo-Enzymatic Methods for the Synthesis of N-Glycans.

Authors:  Qiang Chao; Yi Ding; Zheng-Hui Chen; Meng-Hai Xiang; Ning Wang; Xiao-Dong Gao
Journal:  Front Chem       Date:  2020-06-16       Impact factor: 5.221

7.  Influence of N-glycosylation on effector functions and thermal stability of glycoengineered IgG1 monoclonal antibody with homogeneous glycoforms.

Authors:  Ryuta Wada; Makoto Matsui; Nana Kawasaki
Journal:  MAbs       Date:  2018-12-10       Impact factor: 5.857

Review 8.  On enzymatic remodeling of IgG glycosylation; unique tools with broad applications.

Authors:  Jonathan Sjögren; Rolf Lood; Andreas Nägeli
Journal:  Glycobiology       Date:  2020-03-20       Impact factor: 4.313

Review 9.  Sialylated immunoglobulin G: a promising diagnostic and therapeutic strategy for autoimmune diseases.

Authors:  Danqi Li; Yuchen Lou; Yamin Zhang; Si Liu; Jun Li; Juan Tao
Journal:  Theranostics       Date:  2021-03-13       Impact factor: 11.556

10.  Synthetic Carbohydrate Chemistry and Translational Medicine.

Authors:  Sachin S Shivatare; Chi-Huey Wong
Journal:  J Org Chem       Date:  2020-10-30       Impact factor: 4.354

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.