Literature DB >> 29808523

Effects of robot-assisted gait training in chronic stroke patients treated by botulinum toxin-a: A pivotal study.

Dursun Erbil1, Gokbel Tugba2, Topcu Hasan Murat3, Akarsu Melike4, Akyüz Merve4, Karacan Cagla4, Çiftçi Can Mehmetali3, Öztürk Akay3, Dursun Nigar1.   

Abstract

OBJECTIVE: To investigate combined effects of robot-assisted training (RAT) and physical therapy versus physical therapy only on balance and gait function of chronic stroke patients after botulinum toxin-A (BoNT-A) treatment.
METHODS: Forty-eight chronic stroke patients, received BoNT-A treatment for lower extremity spastic muscles, were randomly assigned to RAT (n = 32) and control (n = 16) groups in a 2:1 ratio. RAT group received 30 min of RAT (RoboGait®) plus 60 min of physical therapy, whereas controls received 90 min of physical therapy for 3 weeks during weekdays. Outcome assessments were measured at baseline and post-treatment Weeks 6 and 12. Spasticity was assessed by Modified Ashworth Scale and Tardieu Scale. Balance and gait functions were assessed by Berg Balance Scale, Timed Up and Go test, and Rivermead Visual Gait Assessment.
RESULTS: Demographic and baseline characteristics were similar in both groups (p > .05) for all parameters. Significant improvements were determined in both RAT and control groups regarding spasticity, balance, and gait functions after treatment. However, at post-treatment Weeks 6 and 12, change from baseline Timed Up and Go test (p = .003 and p = .002, respectively), Berg Balance Scale (p = .001 and p < .001, respectively), and Rivermead Visual Gait Assessment (p < .001 and p < .001, respectively) were significantly higher in RAT group than those of the control group.
CONCLUSION: Integrated treatment with RAT and physical therapy might provide additional benefits in chronic stroke patients whom spasticity was treated by BoNT-A.
Copyright © 2018 John Wiley & Sons, Ltd.

Entities:  

Keywords:  botulinum toxin-a; gait; robotics; stroke

Mesh:

Substances:

Year:  2018        PMID: 29808523     DOI: 10.1002/pri.1718

Source DB:  PubMed          Journal:  Physiother Res Int        ISSN: 1358-2267


  5 in total

1.  Upper limb motor improvement in chronic stroke after combining botulinum toxin A injection and multi-joints robot-assisted therapy: a case report.

Authors:  Alex Martino Cinnera; Alessandra Pucello; Alessandro Lupo; Francesca Gimigliano; Elisa Mammucari; Dario Lo Cicero; Marco Iosa; Stefano Paolucci; Giovanni Morone
Journal:  Oxf Med Case Reports       Date:  2019-10-31

Review 2.  Botulinum Toxin Therapy Combined with Rehabilitation for Stroke: A Systematic Review of Effect on Motor Function.

Authors:  Takatoshi Hara; Ryo Momosaki; Masachika Niimi; Naoki Yamada; Hiroyoshi Hara; Masahiro Abo
Journal:  Toxins (Basel)       Date:  2019-12-05       Impact factor: 4.546

Review 3.  Robotic devices for paediatric rehabilitation: a review of design features.

Authors:  Alberto Gonzalez; Lorenzo Garcia; Jeff Kilby; Peter McNair
Journal:  Biomed Eng Online       Date:  2021-09-06       Impact factor: 2.819

4.  Electromechanical-assisted training for walking after stroke.

Authors:  Jan Mehrholz; Simone Thomas; Joachim Kugler; Marcus Pohl; Bernhard Elsner
Journal:  Cochrane Database Syst Rev       Date:  2020-10-22

5.  Gait training using a hybrid assistive limb after botulinum toxin treatment for cerebral palsy: a case report.

Authors:  Mayumi Matsuda Kuroda; Hirotaka Mutsuzaki; Kenichi Yoshikawa; Haruka Ohguro; Iwasaki Nobuaki
Journal:  J Phys Ther Sci       Date:  2021-06-18
  5 in total

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