| Literature DB >> 29807515 |
Jessika de Oliveira Viana1, Hamilton Mitsugu Ishiki2, Marcus Tullius Scotti1, Luciana Scotti1,3.
Abstract
Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis, which has high levels of mortality worldwide and has already gained resistance to first- and second-line drugs. The study by new chemical entities with promising activities becomes paramount to broaden the therapeutic strategies in the cure of the patients affected with this disease. In this context, in this review we report the discovery of 3 classes of compounds that can simultaneously interact with more than one target of Mycobacterium tuberculosis. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.Entities:
Keywords: Anti tuberculosis drugs; Inhibition; Multi-target drugs; Mycobacterium tuberculosis; Targeting; Tuberculosis.
Mesh:
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Year: 2018 PMID: 29807515 DOI: 10.2174/1568026618666180528124414
Source DB: PubMed Journal: Curr Top Med Chem ISSN: 1568-0266 Impact factor: 3.295