André O Werneck1, Manuel J Coelho-E-Silva2, Camila S Padilha1, Enio R V Ronque1, Edilson S Cyrino1, Célia L Szwarcwald3, Danilo R Silva4. 1. a Study and Research Group in Metabolism, Nutrition, and Exercise - GEPEMENE , State University of Londrina - UEL , Londrina , Brazil. 2. b Faculty of Sports Sciences and Physical Education, University of Coimbra , Coimbra , Portugal. 3. c Fundação Oswaldo Cruz (Fiocruz), Instituto de Comunicação e Informação Científica e Tecnológica em Saúde , Rio de Janeiro , Brazil. 4. d Department of Physical Education , Federal University of Sergipe - UFS , São Cristóvão , Brazil.
Abstract
AIM: The aim was to evaluate the association between age at menarche and cancer using a nationally representative sample of Brazilian women. METHODS: Data from the Brazilian Health Survey (PNS), a nationally representative survey conducted in 2013 (n = 33,715 women; ≥18 years), were used. Information on cancer diagnosis, age at menarche and other co-variables (chronological age, educational status, skin colour, menopause, leisure-time physical activity and tobacco smoking) were collected via interview. Logistic regression models were used for aetiological analyses. RESULTS: The prevalence of cancer diagnosis was greater among women with early age at menarche [2.6% (2.0-3.5%)] compared to on-time [1.6% (1.4-1.9%)] and late women [2.0% (1.1-3.4%)]. The onset of menarche ≤11 years was significantly associated with cancer risk, regardless of co-variables [OR =2.45 (1.34-4.48)], compared to the late group. CONCLUSION: Early age at menarche was associated with cancer risk in adulthood, regardless of race, educational status, chronological age, obesity, menopause onset, tobacco smoking or physical activity.
AIM: The aim was to evaluate the association between age at menarche and cancer using a nationally representative sample of Brazilian women. METHODS: Data from the Brazilian Health Survey (PNS), a nationally representative survey conducted in 2013 (n = 33,715 women; ≥18 years), were used. Information on cancer diagnosis, age at menarche and other co-variables (chronological age, educational status, skin colour, menopause, leisure-time physical activity and tobacco smoking) were collected via interview. Logistic regression models were used for aetiological analyses. RESULTS: The prevalence of cancer diagnosis was greater among women with early age at menarche [2.6% (2.0-3.5%)] compared to on-time [1.6% (1.4-1.9%)] and late women [2.0% (1.1-3.4%)]. The onset of menarche ≤11 years was significantly associated with cancer risk, regardless of co-variables [OR =2.45 (1.34-4.48)], compared to the late group. CONCLUSION: Early age at menarche was associated with cancer risk in adulthood, regardless of race, educational status, chronological age, obesity, menopause onset, tobacco smoking or physical activity.
Entities:
Keywords:
Puberty; adult; menstruation; motor activity; reproductive physiological phenomena