Ji-Hyun Jang1, Myoung Geun Lee2, Jack L Ferracane3, Harry Davis4, Han Eul Bae2, Dongseok Choi5, Duck-Su Kim6. 1. Department of Conservative Dentistry, School of Dentistry, Kyung Hee University, Seoul, 02453, Republic of Korea. 2. Department of Conservative Dentistry, Graduate School, Kyung Hee University, Seoul, 02453, Republic of Korea. 3. Department of Restorative Dentistry, School of Dentistry, Oregon Health & Science University, Portland, OR 97201, USA. 4. Department of Biomaterials and Biomechanics, School of Dentistry, Oregon Health & Science University, Portland, OR, 97201, USA. 5. Division of Biostatistics, Oregon Health and Science University-Portland State University of Public Health, Oregon Health and Science University, Portland, OR, 97239, USA; School of Dentisty, Kyung Hee University, Seoul, 02453, Republic of Korea. 6. Department of Conservative Dentistry, School of Dentistry, Kyung Hee University, Seoul, 02453, Republic of Korea. Electronic address: dentist96@naver.com.
Abstract
OBJECTIVES: The purpose of this study was to evaluate the effect of bioactive glass (BAG)-containing composite on dentin remineralization. METHODS: Sixty-six dentin disks with 3 mm thickness were prepared from thirty-three bovine incisors. The following six experimental groups were prepared according to type of composite (control and experimental) and storage solutions (simulated body fluid [SBF] and phosphate-buffered saline [PBS]): 1 (undemineralized); 2 (demineralized); 3 (demineralized with control composite in SBF); 4 (demineralized with control composite in PBS); 5 (demineralized with experimental composite in SBF); and 6 (demineralized with experimental composite in PBS). BAG65S (65% Si, 31% Ca, and 4% P) was prepared via the sol-gel method. The control composite was made with a 50:50 Bis-GMA:TEGDMA resin matrix, 57 wt% strontium glass, and 15 wt% aerosol silica. The experimental composite had the same resin and filler, but with 15 wt% BAG65S replacing the aerosol silica. For groups 3-6, composite disks (20 × 10 × 2 mm) were prepared and approximated to the dentin disks and stored in PBS or SBF for 2 weeks. Micro-hardness test, attenuated total reflection Fourier-transform infrared spectroscopy (ATR-FTIR) and field-emission scanning electron microscopy (FE-SEM) was investigated. RESULTS: The BAG-containing composite significantly increased the micro-hardness of the adjacent demineralized dentin. ATR-FTIR revealed calcium phosphate peaks on the surface of the groups which used BAG-containing composite. FE-SEM revealed surface deposits partially occluding the dentin surface. No significant difference was found between SBF and PBS storage. CLINICAL SIGNIFICANCE: Bioactive glass is a potentially useful material for remineralization of tooth structure. When incorporated into a resin composite, it may aid in remineralizing the adjacent demineralized dentin, thus preventing further destruction of the tooth. CONCLUSION: BAG-containing composites placed in close proximity can partially remineralize adjacent demineralized dentin.
OBJECTIVES: The purpose of this study was to evaluate the effect of bioactive glass (BAG)-containing composite on dentin remineralization. METHODS:Sixty-six dentin disks with 3 mm thickness were prepared from thirty-three bovine incisors. The following six experimental groups were prepared according to type of composite (control and experimental) and storage solutions (simulated body fluid [SBF] and phosphate-buffered saline [PBS]): 1 (undemineralized); 2 (demineralized); 3 (demineralized with control composite in SBF); 4 (demineralized with control composite in PBS); 5 (demineralized with experimental composite in SBF); and 6 (demineralized with experimental composite in PBS). BAG65S (65% Si, 31% Ca, and 4% P) was prepared via the sol-gel method. The control composite was made with a 50:50 Bis-GMA:TEGDMA resin matrix, 57 wt% strontium glass, and 15 wt% aerosol silica. The experimental composite had the same resin and filler, but with 15 wt% BAG65S replacing the aerosol silica. For groups 3-6, composite disks (20 × 10 × 2 mm) were prepared and approximated to the dentin disks and stored in PBS or SBF for 2 weeks. Micro-hardness test, attenuated total reflection Fourier-transform infrared spectroscopy (ATR-FTIR) and field-emission scanning electron microscopy (FE-SEM) was investigated. RESULTS: The BAG-containing composite significantly increased the micro-hardness of the adjacent demineralized dentin. ATR-FTIR revealed calcium phosphate peaks on the surface of the groups which used BAG-containing composite. FE-SEM revealed surface deposits partially occluding the dentin surface. No significant difference was found between SBF and PBS storage. CLINICAL SIGNIFICANCE: Bioactive glass is a potentially useful material for remineralization of tooth structure. When incorporated into a resin composite, it may aid in remineralizing the adjacent demineralized dentin, thus preventing further destruction of the tooth. CONCLUSION: BAG-containing composites placed in close proximity can partially remineralize adjacent demineralized dentin.