Literature DB >> 29804078

Spinal tophaceous gout presenting in a young adult without pain.

Zaid Al-Jebaje1, John Mellon Elibol2, Jonathan Peters3, Ali Alameri1.   

Abstract

A 26-year-old man with a medical history of gout and morbid obesity presented with a 7-day history of decreased sensation to light touch and temperature from the feet to the level of the nipples. He also noted incomplete voiding. Laboratory investigations showed an elevated serum uric acid level (10.4 mg/dL, reference range: 3.8-8.7 mg/dL) as well as negative rapid plasma reagin and rheumatoid factor. MRI showed inflammatory changes on multiple spinal levels. Laminectomy was performed, with follow-up biopsy revealing multiple multinucleated giant cells and monosodium urate (MSU) crystals. He was ultimately diagnosed with spinal gout. Patient's symptoms did not resolve immediately after surgery. Yet with the administration of intravenous glucocorticoids and a course of non-steroidal anti-inflammatory drugs, he slowly regained sensation, leaving the hospital with complete resolution of symptoms. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Entities:  

Keywords:  musculoskeletal and joint disorders; neurological injury; neurology

Mesh:

Year:  2018        PMID: 29804078      PMCID: PMC5976080          DOI: 10.1136/bcr-2018-224406

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  15 in total

Review 1.  Tophaceous gout of the spine: case report and review of the literature.

Authors:  Frederic Marinho; Delphine Zeitoun-Eiss; Jerôme Renoux; Jean-Louis Brasseur; Catherine Genestie; Philippe Grenier
Journal:  J Neuroradiol       Date:  2011-06-08       Impact factor: 3.447

Review 2.  Cervical spondylotic myelopathy in the young adult: a review of the literature and clinical diagnostic criteria in an uncommon demographic.

Authors:  Peter S Amenta; George M Ghobrial; Kelly Krespan; Phi Nguyen; Muhammed Ali; James S Harrop
Journal:  Clin Neurol Neurosurg       Date:  2014-03-02       Impact factor: 1.876

3.  Spinal gout: case report and review of the literature.

Authors:  Mirela Draganescu; Lawrence J Leventhal
Journal:  J Clin Rheumatol       Date:  2004-04       Impact factor: 3.517

4.  2012 American College of Rheumatology guidelines for management of gout. Part 2: therapy and antiinflammatory prophylaxis of acute gouty arthritis.

Authors:  Dinesh Khanna; Puja P Khanna; John D Fitzgerald; Manjit K Singh; Sangmee Bae; Tuhina Neogi; Michael H Pillinger; Joan Merill; Susan Lee; Shraddha Prakash; Marian Kaldas; Maneesh Gogia; Fernando Perez-Ruiz; Will Taylor; Frédéric Lioté; Hyon Choi; Jasvinder A Singh; Nicola Dalbeth; Sanford Kaplan; Vandana Niyyar; Danielle Jones; Steven A Yarows; Blake Roessler; Gail Kerr; Charles King; Gerald Levy; Daniel E Furst; N Lawrence Edwards; Brian Mandell; H Ralph Schumacher; Mark Robbins; Neil Wenger; Robert Terkeltaub
Journal:  Arthritis Care Res (Hoboken)       Date:  2012-10       Impact factor: 4.794

Review 5.  Gout in the spine.

Authors:  Eduardo Massato Hasegawa; Filipe Martins de Mello; Cláudia Goldenstein-Schainberg; Ricardo Fuller
Journal:  Rev Bras Reumatol       Date:  2013 May-Jun

6.  Correlates of axial gout: a cross-sectional study.

Authors:  Rukmini M Konatalapalli; Elena Lumezanu; James S Jelinek; Mark D Murphey; Hong Wang; Arthur Weinstein
Journal:  J Rheumatol       Date:  2012-04-15       Impact factor: 4.666

7.  Spinal gout tophus: a very rare cause of radiculopathy.

Authors:  Askin Esen Hasturk; Mehmet Basmaci; Suat Canbay; Cigdem Vural; Fuat Erten
Journal:  Eur Spine J       Date:  2011-05-19       Impact factor: 3.134

Review 8.  Epidemiology of gout.

Authors:  Edward Roddy; Hyon K Choi
Journal:  Rheum Dis Clin North Am       Date:  2014-02-19       Impact factor: 2.670

9.  Spinal gout: A review with case illustration.

Authors:  Hossein Elgafy; Xiaochen Liu; Joseph Herron
Journal:  World J Orthop       Date:  2016-11-18

Review 10.  Dual-energy CT in gout - A review of current concepts and applications.

Authors:  Hong Chou; Teck Yew Chin; Wilfred C G Peh
Journal:  J Med Radiat Sci       Date:  2017-02-26
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