Elio Prestipino1, Martina Squitieri1, Lorenzo Razzolini2, Luisa Pastò1, Paolo Forleo1, Maria Pia Amato1. 1. University of Florence, NUEROFARBA Department, Neuroscience section, Viale Pieraccini 6, 50139, Florence, Italy. 2. University of Florence, NUEROFARBA Department, Neuroscience section, Viale Pieraccini 6, 50139, Florence, Italy. Electronic address: lorenzo.razzolini@alice.it.
Abstract
BACKGROUND: We report a case of a woman affected by relapsing remitting Multiple Sclerosis who developed acute left ventricular dysfunction in the context of a severe brainstem relapse, one month after an attempt of in-vitro fertilization. DISCUSSION: The characteristics of our case are consistent with the hypothesis of a possible causal association between an acute medulla oblongata lesion and the occurrence of Takotsubo cardiomyopathy. CONCLUSION: Our case adds to previous reports in this field and calls for awareness of this exceptional extra-neurological manifestation of MS. It seems also to confirm the possible association between MS relapses and ovarian stimulation.
BACKGROUND: We report a case of a woman affected by relapsing remitting Multiple Sclerosis who developed acute left ventricular dysfunction in the context of a severe brainstem relapse, one month after an attempt of in-vitro fertilization. DISCUSSION: The characteristics of our case are consistent with the hypothesis of a possible causal association between an acute medulla oblongata lesion and the occurrence of Takotsubo cardiomyopathy. CONCLUSION: Our case adds to previous reports in this field and calls for awareness of this exceptional extra-neurological manifestation of MS. It seems also to confirm the possible association between MS relapses and ovarian stimulation.