| Literature DB >> 29803936 |
Abstract
How can small-to-medium pharma and biotech companies enhance the chances of running a successful drug project and maximise the return on a limited number of assets? Having a full appreciation of the safety risks associated with proposed drug targets is a crucial element in understanding the unwanted side-effects that might stop a project in its tracks. Having this information is necessary to complement knowledge about the probable efficacy of a future drug. However, the lack of data-rich insight into drug-target safety is one of the major causes of drug-project failure today. Conducting comprehensive target-safety reviews early in the drug discovery process enables project teams to make the right decisions about which drug targets to take forward.Mesh:
Year: 2018 PMID: 29803936 DOI: 10.1016/j.drudis.2018.05.028
Source DB: PubMed Journal: Drug Discov Today ISSN: 1359-6446 Impact factor: 7.851