Literature DB >> 29802946

Phytochemicals, pharmacology, clinical application, patents, and products of Amomi fructus.

Sizhuo Suo1, Yunfeng Lai2, Meng Li3, Qirui Song4, Jing Cai5, Jing Zhao6, Qing Yang7, Carolina Oi Lam Ung8, Hao Hu9.   

Abstract

Amomi fructus (A. fructus) (Sharen) is a well-known traditional Chinese medicine widely used to treat gastrointestinal diseases. It has high medical and economic values, which have been confirmed both in vitro and in vivo studies. This review highlights the phytochemicals, pharmacology, clinical application, patents, and products of A. fructus. More than 100 phytochemicals have been isolated and identified from A. fructus, mainly including volatile oils, saponins, flavonoids, organic acids, inorganic ingredients, and polysaccharides. The main pharmacology of gastrointestinal protection, anti-inflammatory activity, analgesic activity, antidiarrheal activity, antibacterial activity, anti-microbial activity and hypoglycemic activity have been confirmed. The main clinical applications include functional digestion disorder, gastritis, helicobacter pylori infection in children and treatment of mastitis. There are 23 patents and 405 different drug products of A. fructus.
Copyright © 2018 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Amomi fructus; Clinical application; Patents and products; Pharmacology; Phytochemicals

Mesh:

Substances:

Year:  2018        PMID: 29802946     DOI: 10.1016/j.fct.2018.05.051

Source DB:  PubMed          Journal:  Food Chem Toxicol        ISSN: 0278-6915            Impact factor:   6.023


  11 in total

1.  Network pharmacology and experimental verification based research into the effect and mechanism of Aucklandiae Radix-Amomi Fructus against gastric cancer.

Authors:  Siyuan Song; Jiayu Zhou; Ye Li; Jiatong Liu; Jingzhan Li; Peng Shu
Journal:  Sci Rep       Date:  2022-06-07       Impact factor: 4.996

2.  The Absorption Characteristics of Nonvolatile Components in a Water Extraction From Amomi fructus as Determined by In Situ Single-Pass Intestinal Perfusion and High-Performance Liquid Chromatography.

Authors:  Yuebao Yao; Wenjuan Mi; Guangzhao Cao; Ruiqi Yang; Huirong Chen; Yong Liu; Huiqin Zou; Yonghong Yan
Journal:  Front Pharmacol       Date:  2020-06-05       Impact factor: 5.810

3.  Ethyl Acetate Fraction of Amomum xanthioides Ameliorates Nonalcoholic Fatty Liver Disease in a High-Fat Diet Mouse Model.

Authors:  Hwi-Jin Im; Seung-Ju Hwang; Jin-Seok Lee; Sung-Bae Lee; Ji-Yun Kang; Chang-Gue Son
Journal:  Nutrients       Date:  2020-08-13       Impact factor: 5.717

4.  Comparison of volatile compounds in different parts of fresh Amomum villosum Lour. from different geographical areas using cryogenic grinding combined HS-SPME-GC-MS.

Authors:  Ling-Xiao Chen; Yun-Feng Lai; Wei-Xiong Zhang; Jing Cai; Hao Hu; Ying Wang; Jing Zhao; Shao-Ping Li
Journal:  Chin Med       Date:  2020-09-07       Impact factor: 5.455

5.  Reversine and herbal Xiang-Sha-Liu-Jun-Zi decoction ameliorate thioacetamide-induced hepatic injury by regulating the RelA/NF-κB/caspase signaling pathway.

Authors:  Zhen-Hao Mai; Yu Huang; Di Huang; Zi-Sheng Huang; Zhi-Xiang He; Pei-Lin Li; Shuai Zhang; Jie-Feng Weng; Wei-Li Gu
Journal:  Open Life Sci       Date:  2020-09-15       Impact factor: 0.938

6.  The complete chloroplast genome sequence of Amomum villosum Lour.

Authors:  Mengli Ma; Bingyue Lu
Journal:  Mitochondrial DNA B Resour       Date:  2020-02-03       Impact factor: 0.658

Review 7.  Reenvisioning Traditional to Regenerative Therapeutic Advances in Managing Nonalcoholic Fatty Liver Disease in Diabetes Mellitus.

Authors:  Lung-Wen Tsai; Yi-Hsiang Lu; Rajni Dubey; Jeng-Fong Chiou
Journal:  J Diabetes Res       Date:  2021-11-11       Impact factor: 4.011

8.  Efficacy and Safety of Shenqu Xiaoshi Oral Liquid Compared With Domperidone Syrup in Children With Functional Dyspepsia.

Authors:  Yi Yu; Xiao-Li Xie; Jie Wu; Zhong-Yue Li; Zhi-Gang He; Chun-Jie Liang; Zhong-Qin Jin; Ai-Zhen Wang; Jian Gu; Ying Huang; Hong Mei; Wei Shi; Si-Yuan Hu; Xun Jiang; Juan Du; Chi-Jun Hu; Li Gu; Mao-Lin Jiang; Zhi-Qin Mao; Chun-Di Xu
Journal:  Front Pharmacol       Date:  2022-02-04       Impact factor: 5.810

9.  Effect of Amomum villosum essential oil as an additive on the chemical composition, fermentation quality, and bacterial community of paper mulberry silage.

Authors:  Maoya Li; Xueying Fan; Qiming Cheng; Yulian Chen; Jianhua Long; Yao Lei; Ping Li; Chao Chen
Journal:  Front Microbiol       Date:  2022-07-22       Impact factor: 6.064

10.  Purification, Structural Characterization and Immunomodulatory Effects of Polysaccharides from Amomumvillosum Lour. on RAW 264.7 Macrophages.

Authors:  Yang Zhou; Chunguo Qian; Depo Yang; Cailin Tang; Xinjun Xu; E-Hu Liu; Jingtang Zhong; Longping Zhu; Zhimin Zhao
Journal:  Molecules       Date:  2021-05-02       Impact factor: 4.411

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