Literature DB >> 29802807

ER stress and unfolded protein response in ocular health and disease.

Heike Kroeger1, Wei-Chieh Chiang1, Julia Felden2, Amanda Nguyen1, Jonathan H Lin1,3.   

Abstract

The human eye is the organ that is able to react to light in order to provide sharp three-dimensional and colored images. Unfortunately, the health of the eye can be impacted by various stimuli that can lead to vision loss, such as environmental changes, genetic mutations, or aging. Endoplasmic reticulum (ER) stress and unfolded protein response (UPR) signaling have been detected in many diverse ocular diseases, and chemical and genetic approaches to modulate ER stress and specific UPR regulatory molecules have shown beneficial effects in animal models of eye disease. This review highlights specific eye diseases associated with ER stress and UPR activity, based on a recent symposia exploring this theme. Published 2018. This article is a U.S. Government work and is in the public domain in the USA.

Entities:  

Keywords:  zzm321990AMDzzm321990; zzm321990RGCzzm321990; zzm321990RPEzzm321990; zzm321990UPRzzm321990; zzm321990VEGFzzm321990; ER stress; achromatopsia; glaucoma; neurodegernation; retinal degeneration

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Year:  2018        PMID： 29802807      PMCID： PMC6583901          DOI： 10.1111/febs.14522

Source DB:  PubMed          Journal:  FEBS J        ISSN： 1742-464X            Impact factor:   5.542


  113 in total

Review 1.  BiP binding keeps ATF6 at bay.

Authors:  Thomas Sommer; Ernst Jarosch
Journal:  Dev Cell       Date:  2002-07       Impact factor: 12.270

2.  Reduction of ER stress via a chemical chaperone prevents disease phenotypes in a mouse model of primary open angle glaucoma.

Authors:  Gulab S Zode; Markus H Kuehn; Darryl Y Nishimura; Charles C Searby; Kabhilan Mohan; Sinisa D Grozdanic; Kevin Bugge; Michael G Anderson; Abbot F Clark; Edwin M Stone; Val C Sheffield
Journal:  J Clin Invest       Date:  2011-08-08       Impact factor: 14.808

3.  Damage to the endoplasmic reticulum and activation of apoptotic machinery by oxidative stress in ischemic neurons.

Authors:  Takeshi Hayashi; Atsushi Saito; Shuzo Okuno; Michel Ferrand-Drake; Robert L Dodd; Pak H Chan
Journal:  J Cereb Blood Flow Metab       Date:  2005-01       Impact factor: 6.200

4.  Stress-independent activation of XBP1s and/or ATF6 reveals three functionally diverse ER proteostasis environments.

Authors:  Matthew D Shoulders; Lisa M Ryno; Joseph C Genereux; James J Moresco; Patricia G Tu; Chunlei Wu; John R Yates; Andrew I Su; Jeffery W Kelly; R Luke Wiseman
Journal:  Cell Rep       Date:  2013-04-11       Impact factor: 9.423

5.  Induction of endoplasmic reticulum stress genes, BiP and chop, in genetic and environmental models of retinal degeneration.

Authors:  Heike Kroeger; Carissa Messah; Kelly Ahern; Jason Gee; Victory Joseph; Michael T Matthes; Douglas Yasumura; Marina S Gorbatyuk; Wei-Chieh Chiang; Matthew M LaVail; Jonathan H Lin
Journal:  Invest Ophthalmol Vis Sci       Date:  2012-11-09       Impact factor: 4.799

Review 6.  Primary open-angle glaucoma.

Authors:  Young H Kwon; John H Fingert; Markus H Kuehn; Wallace L M Alward
Journal:  N Engl J Med       Date:  2009-03-12       Impact factor: 91.245

7.  ER stress is involved in T17M rhodopsin-induced retinal degeneration.

Authors:  Mansi M Kunte; Shreyasi Choudhury; Jessica F Manheim; Vishal M Shinde; Masayuki Miura; Vince A Chiodo; William W Hauswirth; Oleg S Gorbatyuk; Marina S Gorbatyuk
Journal:  Invest Ophthalmol Vis Sci       Date:  2012-06-20       Impact factor: 4.799

Review 8.  ER stress and apoptosis: a new mechanism for retinal cell death.

Authors:  Guangjun Jing; Joshua J Wang; Sarah X Zhang
Journal:  Exp Diabetes Res       Date:  2011-12-14

9.  Susceptibility to neurodegeneration in a glaucoma is modified by Bax gene dosage.

Authors:  Richard T Libby; Yan Li; Olga V Savinova; Joseph Barter; Richard S Smith; Robert W Nickells; Simon W M John
Journal:  PLoS Genet       Date:  2005-07-25       Impact factor: 5.917

10.  Ablation of the proapoptotic genes CHOP or Ask1 does not prevent or delay loss of visual function in a P23H transgenic mouse model of retinitis pigmentosa.

Authors:  Adeseye Adekeye; Mohammad Haeri; Eduardo Solessio; Barry E Knox
Journal:  PLoS One       Date:  2014-02-11       Impact factor: 3.240
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  34 in total

1.  Sodium fluoride induces apoptosis and autophagy via the endoplasmic reticulum stress pathway in MC3T3-E1 osteoblastic cells.

Authors:  Xueyan Li; Li Meng; Feng Wang; Xiaojie Hu; Youcheng Yu
Journal:  Mol Cell Biochem       Date:  2018-12-05       Impact factor: 3.396

2.  Japanese Encephalitis Virus Induces Apoptosis and Encephalitis by Activating the PERK Pathway.

Authors:  Qianruo Wang; Xiu Xin; Ting Wang; Yuxin Tang; Shanshan Li; Lingbao Kong; Jiawu Wan; Yangtao Ou; Zibing Yang; Qijia Yu; Liting Zhu; Yunli Guo; Yinsheng Wu; Zhen Ding; Yanni Zhang; Zishu Pan
Journal:  J Virol       Date:  2019-08-13       Impact factor: 5.103

Review 3.  Unfolded Protein Response supports endothelial barrier function.

Authors:  Nektarios Barabutis
Journal:  Biochimie       Date:  2019-08-09       Impact factor: 4.079

4.  Taurine protects R28 cells from hypoxia/re-oxygenation-induced damage via regulation of mitochondrial energy metabolism.

Authors:  Wei Lu; Yuting Yang; Shunxiang Gao; Jihong Wu; Xinghuai Sun
Journal:  Amino Acids       Date:  2022-09-02       Impact factor: 3.789

5.  Toll-like receptor 2 (TLR2) engages endoplasmic reticulum stress sensor IRE1α to regulate retinal innate responses in Staphylococcus aureus endophthalmitis.

Authors:  Ajay Kumar; Pawan Kumar Singh; Kezhong Zhang; Ashok Kumar
Journal:  FASEB J       Date:  2020-08-19       Impact factor: 5.191

6.  Expression of the Endoplasmic Reticulum Stress Marker GRP78 in the Normal Retina and Retinal Degeneration Induced by Blue LED Stimuli in Mice.

Authors:  Yong Soo Park; Hong-Lim Kim; Seung Hee Lee; Yan Zhang; In-Beom Kim
Journal:  Cells       Date:  2021-04-23       Impact factor: 6.600

7.  Traumatic Optic Neuropathy Is Associated with Visual Impairment, Neurodegeneration, and Endoplasmic Reticulum Stress in Adolescent Mice.

Authors:  Shelby M Hetzer; Fernanda Guilhaume-Correa; Dylan Day; Alicia Bedolla; Nathan K Evanson
Journal:  Cells       Date:  2021-04-23       Impact factor: 6.600

8.  Proteostasis Regulators Restore Function of Epilepsy-Associated GABAA Receptors.

Authors:  Xiao-Jing Di; Ya-Juan Wang; Edmund Cotter; Meng Wang; Angela L Whittsette; Dong-Yun Han; Panjamaporn Sangwung; Renae Brown; Joseph W Lynch; Angelo Keramidas; Ting-Wei Mu
Journal:  Cell Chem Biol       Date:  2020-09-03       Impact factor: 8.116

Review 9.  Molecular Mechanisms Related to Oxidative Stress in Retinitis Pigmentosa.

Authors:  Carla Enrica Gallenga; Maria Lonardi; Sofia Pacetti; Sara Silvia Violanti; Paolo Tassinari; Francesco Di Virgilio; Mauro Tognon; Paolo Perri
Journal:  Antioxidants (Basel)       Date:  2021-05-26

10.  Role of VEGFR2 in Mediating Endoplasmic Reticulum Stress Under Glucose Deprivation and Determining Cell Death, Oxidative Stress, and Inflammatory Factor Expression.

Authors:  Bohan Xu; Linbin Zhou; Qishan Chen; Jianing Zhang; Lijuan Huang; Shasha Wang; Zhimin Ye; Xiangrong Ren; Yu Cai; Lasse Dahl Jensen; Weirong Chen; Xuri Li; Rong Ju
Journal:  Front Cell Dev Biol       Date:  2021-06-18
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