Literature DB >> 29802655

Synthesis of 1-Aminoindenes through Aza-Prins-Type Cyclization.

Jian-Fei Bai1, Kento Yasumoto1, Taichi Kano1, Keiji Maruoka1,2.   

Abstract

An acid-catalyzed aza-Prins-type endo cyclization of 2-alkenylbenzaldehydes with BocNH2 or aniline derivatives through in situ generation of iminium intermediates has been developed, and various 1-aminoindene derivatives were readily obtained. The first catalytic asymmetric variant of the present reaction has also been demonstrated.
© 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  Brønsted acids; amines; asymmetric catalysis; cyclization; imines

Year:  2018        PMID: 29802655     DOI: 10.1002/chem.201802448

Source DB:  PubMed          Journal:  Chemistry        ISSN: 0947-6539            Impact factor:   5.236


  1 in total

1.  Mechanism of the Fe(iii)-catalyzed synthesis of hexahydropyrimidine with α-phenylstyrene: a DFT study.

Authors:  Yaxuan Cheng; Siwei Yang; Chaoyu Zhao; Huiling Liu
Journal:  RSC Adv       Date:  2022-07-15       Impact factor: 4.036

  1 in total

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