Literature DB >> 29802139

An exploration of bioactive peptides: My collaboration with Ervin G. Erdös.

Rajko Igić1.   

Abstract

This paper provides a brief historical sketch of the science of biologically active peptides. It also offers the story of how Ervin G. Erdös, a pioneer in the study of metabolism of various peptides, influenced me through collaborations that span many years. I worked in Dr. Erdös's research laboratories in Oklahoma City, Dallas, and Chicago, and we shared research interests through visits across the Atlantic between the former Yugoslavia and the United States. Among other findings, we discovered angiotensin-converting enzyme in the retina, which opened up a new research direction for many scientists interested in serious ocular diseases. This tribute to my mentor paints a portrait of a man who, in addition to his dedication to science and his seminal discoveries about the metabolism of peptides, took the time to invest in training many young scientists. His fine personal qualities explain why all of those who worked with him hold him in such high regard.
© 2018 Igić.

Entities:  

Keywords:  Ervin G. Erdös; angiotensin; angiotensin II; angiotensin-converting enzyme (ACE); kallikrein; kallikrein-kinin; kinase II; renin angiotensin system; retina substance P; vascular biology

Mesh:

Substances:

Year:  2018        PMID: 29802139      PMCID: PMC5971463          DOI: 10.1074/jbc.X118.003433

Source DB:  PubMed          Journal:  J Biol Chem        ISSN: 0021-9258            Impact factor:   5.157


  28 in total

1.  AN IMPROVED MICROBATH.

Authors:  J H GADDUM
Journal:  Br J Pharmacol Chemother       Date:  1964-12

2.  Instrument for recording isotonic contractions of smooth muscles.

Authors:  E G ERDOS; V JACKMAN; W C BARNES
Journal:  J Appl Physiol       Date:  1962-03       Impact factor: 3.531

3.  Hypotensive peptides.

Authors:  E G Erdös
Journal:  Science       Date:  1966-05-27       Impact factor: 47.728

4.  Postgraduate studies (1978-1985) at the Medical Faculty of the University of Tuzla, Tuzla, Bosnia and Herzegovina.

Authors:  Husref Tahirović
Journal:  Acta Med Acad       Date:  2015

5.  Angiotensin I converting enzyme (kininase II) in ocular tissues.

Authors:  R Igić; V Kojović
Journal:  Exp Eye Res       Date:  1980-03       Impact factor: 3.467

Review 6.  Four decades of ocular renin-angiotensin and kallikrein-kinin systems (1977-2017).

Authors:  Rajko Igić
Journal:  Exp Eye Res       Date:  2017-05-23       Impact factor: 3.467

7.  Angiotensin I converting enzyme (kininase II) in isolated retinal microvessels.

Authors:  P E Ward; T A Stewart; K J Hammon; R C Reynolds; R P Igic
Journal:  Life Sci       Date:  1979-04-09       Impact factor: 5.037

8.  Substance P inactivation by aqueous humor.

Authors:  R Igić
Journal:  Exp Eye Res       Date:  1993-10       Impact factor: 3.467

9.  Metabolism of bradykinin by peptidases in the lung.

Authors:  T Dragović; R Igić; E G Erdös; S F Rabito
Journal:  Am Rev Respir Dis       Date:  1993-06

10.  Twenty five years of antismoking movement started by medical students: some further goals.

Authors:  S Zizic-Borjanovic; M Jerinic; R Igic
Journal:  J BUON       Date:  2007 Apr-Jun       Impact factor: 2.533

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