Literature DB >> 29800267

Non-coding RNAs in vascular disease - from basic science to clinical applications: scientific update from the Working Group of Myocardial Function of the European Society of Cardiology.

Jan Fiedler1, Andrew H Baker2, Stefanie Dimmeler3, Stephane Heymans4,5,6, Manuel Mayr7, Thomas Thum1,8,9.   

Abstract

Non-coding RNAs are increasingly recognized not only as regulators of various biological functions but also as targets for a new generation of RNA therapeutics and biomarkers. We hereby review recent insights relating to non-coding RNAs including microRNAs (e.g. miR-126, miR-146a), long non-coding RNAs (e.g. MIR503HG, GATA6-AS, SMILR), and circular RNAs (e.g. cZNF292) and their role in vascular diseases. This includes identification and therapeutic use of hypoxia-regulated non-coding RNAs and endogenous non-coding RNAs that regulate intrinsic smooth muscle cell signalling, age-related non-coding RNAs, and non-coding RNAs involved in the regulation of mitochondrial biology and metabolic control. Finally, we discuss non-coding RNA species with biomarker potential.This article is part of the Mini Review Series from the Varenna 2017 meeting of the Working Group of Myocardial Function of the European Society of Cardiology.

Entities:  

Mesh：

Substances：

Year:  2018        PMID： 29800267      PMCID： PMC6054241          DOI： 10.1093/cvr/cvy121

Source DB:  PubMed          Journal:  Cardiovasc Res        ISSN： 0008-6363            Impact factor:   10.787


  41 in total

1.  Translational Regulation of the Mitochondrial Genome Following Redistribution of Mitochondrial MicroRNA in the Diabetic Heart.

Authors:  Rajaganapathi Jagannathan; Dharendra Thapa; Cody E Nichols; Danielle L Shepherd; Janelle C Stricker; Tara L Croston; Walter A Baseler; Sara E Lewis; Ivan Martinez; John M Hollander
Journal:  Circ Cardiovasc Genet       Date:  2015-09-16

2.  Inhibition of MicroRNA-146a and Overexpression of Its Target Dihydrolipoyl Succinyltransferase Protect Against Pressure Overload-Induced Cardiac Hypertrophy and Dysfunction.

Authors:  Ward A Heggermont; Anna-Pia Papageorgiou; Annelies Quaegebeur; Sophie Deckx; Paolo Carai; Wouter Verhesen; Guy Eelen; Sandra Schoors; Rick van Leeuwen; Sergey Alekseev; Ies Elzenaar; Stefan Vinckier; Peter Pokreisz; Ann-Sophie Walravens; Rik Gijsbers; Chris Van Den Haute; Alexander Nickel; Blanche Schroen; Marc van Bilsen; Stefan Janssens; Christoph Maack; Yigal Pinto; Peter Carmeliet; Stephane Heymans
Journal:  Circulation       Date:  2017-06-13       Impact factor: 29.690

3.  Long Noncoding RNA Meg3 Controls Endothelial Cell Aging and Function: Implications for Regenerative Angiogenesis.

Authors:  Reinier A Boon; Patrick Hofmann; Katharina M Michalik; Noelia Lozano-Vidal; Denise Berghäuser; Ariane Fischer; Andrea Knau; Nicolas Jaé; Christoph Schürmann; Stefanie Dimmeler
Journal:  J Am Coll Cardiol       Date:  2016-12-13       Impact factor: 24.094

4.  MicroRNA-Based Therapy of GATA2-Deficient Vascular Disease.

Authors:  Dorothee Hartmann; Jan Fiedler; Kristina Sonnenschein; Annette Just; Angelika Pfanne; Karina Zimmer; Janet Remke; Ariana Foinquinos; Malte Butzlaff; Katharina Schimmel; Lars Maegdefessel; Denise Hilfiker-Kleiner; Nico Lachmann; Andreas Schober; Natali Froese; Jörg Heineke; Johann Bauersachs; Sandor Batkai; Thomas Thum
Journal:  Circulation       Date:  2016-10-25       Impact factor: 29.690

5.  A cardiac-enriched microRNA, miR-378, blocks cardiac hypertrophy by targeting Ras signaling.

Authors:  Raghu S Nagalingam; Nagalingam R Sundaresan; Mahesh P Gupta; David L Geenen; R John Solaro; Madhu Gupta
Journal:  J Biol Chem       Date:  2013-02-27       Impact factor: 5.157

6.  Preclinical Development of a MicroRNA-Based Therapy for Elderly Patients With Myocardial Infarction.

Authors:  Shashi Kumar Gupta; Ariana Foinquinos; Sabrina Thum; Janet Remke; Karina Zimmer; Christophe Bauters; Pascal de Groote; Reinier A Boon; Leon J de Windt; Sebastian Preissl; Lutz Hein; Sandor Batkai; Florence Pinet; Thomas Thum
Journal:  J Am Coll Cardiol       Date:  2016-10-04       Impact factor: 24.094

7.  Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013.

Authors: 
Journal:  Lancet       Date:  2014-12-18       Impact factor: 79.321

8.  Quaking Inhibits Doxorubicin-Mediated Cardiotoxicity Through Regulation of Cardiac Circular RNA Expression.

Authors:  Shashi Kumar Gupta; Ankita Garg; Christian Bär; Shambhabi Chatterjee; Ariana Foinquinos; Hendrik Milting; Katrin Streckfuß-Bömeke; Jan Fiedler; Thomas Thum
Journal:  Circ Res       Date:  2017-11-13       Impact factor: 17.367

9.  Mitochondria Associated MicroRNA Expression Profiling of Heart Failure.

Authors:  Xiaoxia Wang; Chun Song; Xiao Zhou; Xiaorui Han; Jun Li; Zengwu Wang; Haibao Shang; Yuli Liu; Huiqing Cao
Journal:  Biomed Res Int       Date:  2017-09-24       Impact factor: 3.411

10.  The lncRNA GATA6-AS epigenetically regulates endothelial gene expression via interaction with LOXL2.

Authors:  Philipp Neumann; Nicolas Jaé; Andrea Knau; Simone F Glaser; Youssef Fouani; Oliver Rossbach; Marcus Krüger; David John; Albrecht Bindereif; Phillip Grote; Reinier A Boon; Stefanie Dimmeler
Journal:  Nat Commun       Date:  2018-01-16       Impact factor: 14.919
View more
  11 in total

1.  Knockdown of circular RNA hsa_circ_0062270 suppresses the progression of melanoma via downregulation of CDC45.

Authors:  Tian Hao; Yi Yang; Juan He; Jia Bai; Yongjian Zheng; Zhanpeng Luo
Journal:  Histol Histopathol       Date:  2021-12-21       Impact factor: 2.303

2.  What matters in Cardiovascular Research? Scientific discovery driving clinical delivery.

Authors:  Tomasz J Guzik; Charalambos Antoniades; Andrew H Baker; David G Harrison; Christopher M Loughrey; Pasquale Maffia; Elizabeth Murphy; Stuart A Nicklin; Karlheinz Peter; Jeremy Pearson; Barbara Casadei
Journal:  Cardiovasc Res       Date:  2018-10-01       Impact factor: 10.787

Review 3.  Leveraging clinical epigenetics in heart failure with preserved ejection fraction: a call for individualized therapies.

Authors:  Nazha Hamdani; Sarah Costantino; Andreas Mügge; Djamel Lebeche; Carsten Tschöpe; Thomas Thum; Francesco Paneni
Journal:  Eur Heart J       Date:  2021-05-21       Impact factor: 29.983

4.  FGF21 alleviates pulmonary hypertension by inhibiting mTORC1/EIF4EBP1 pathway via H19.

Authors:  Xiuchun Li; Yaxin Zhang; Lihuang Su; Luqiong Cai; Chi Zhang; Jianhao Zhang; Junwei Sun; Mengyu Chai; Mengsi Cai; Qian Wu; Chi Zhang; Xiaoqing Yan; Liangxing Wang; Xiaoying Huang
Journal:  J Cell Mol Med       Date:  2022-04-19       Impact factor: 5.295

5.  LncRNA MIR503HG inhibits cell migration and invasion via miR-103/OLFM4 axis in triple negative breast cancer.

Authors:  Jia Fu; Guanjun Dong; Hui Shi; Junfeng Zhang; Zhaochen Ning; Xingna Bao; Chenjie Liu; Jing Hu; Minghui Liu; Bin Xiong
Journal:  J Cell Mol Med       Date:  2019-05-06       Impact factor: 5.310

Review 6.  Regulatory RNAs in Heart Failure.

Authors:  Clarissa Pedrosa Costa Gomes; Blanche Schroen; Gabriela M Kuster; Emma L Robinson; Kerrie Ford; Iain B Squire; Stephane Heymans; Fabio Martelli; Costanza Emanueli; Yvan Devaux
Journal:  Circulation       Date:  2020-01-27       Impact factor: 29.690

7.  Microarray analysis of the time-dependent expression profiles of long non-coding RNAs in the progression of vein graft stenotic disease.

Authors:  Jiayu Shen; Hongwei Zhang; Chen Lu; Jun Gu; Yu Zhang; Jia Hu
Journal:  Exp Ther Med       Date:  2021-04-15       Impact factor: 2.447

Review 8.  Emerging Potential of Exosomal Non-coding RNA in Parkinson's Disease: A Review.

Authors:  Peng Zhang; Madiha Rasheed; Junhan Liang; Chaolei Wang; Lin Feng; Zixuan Chen
Journal:  Front Aging Neurosci       Date:  2022-03-10       Impact factor: 5.750

9.  Circulating miR-206 and Wnt-signaling are associated with cardiovascular complications and a history of preeclampsia in women.

Authors:  Kenny Schlosser; Amanpreet Kaur; Natalie Dayan; Duncan J Stewart; Louise Pilote; Christian Delles
Journal:  Clin Sci (Lond)       Date:  2020-01-31       Impact factor: 6.124

Review 10.  MicroRNA-34a: the bad guy in age-related vascular diseases.

Authors:  Angela Raucci; Federica Macrì; Stefania Castiglione; Ileana Badi; Maria Cristina Vinci; Estella Zuccolo
Journal:  Cell Mol Life Sci       Date:  2021-10-26       Impact factor: 9.261
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.