Literature DB >> 29800022

Identification of Phenotypic Patterns of Dysphagia: A Proof of Concept Study.

Kendrea L Focht Garand1, Kent E Armeson2, Elizabeth G Hill3, Bonnie Martin-Harris4.   

Abstract

Purpose: The purpose of the current project was to explore the feasibility for subtyping dysphagia traits or patterns of scores in a subset of data from the Modified Barium Swallow Impairment Profile global registry in patients referred to videofluoroscopic swallowing studies across 5 common medical categories: (a) cardiothoracic, (b) gastroenterology, (c) head and neck cancer, (d) neurology, and (e) pulmonary. Method: Videofluoroscopic swallowing study imaging and Modified Barium Swallow Impairment Profile metrics were used to evaluate 235 patients with dysphagia grouped into 1 of the 5 categories. Two summative domain scores (oral total [OT] and pharyngeal total [PT]) and 17 component scores were tested for differences among the categories.
Results: When compared with the gastroenterology category, significantly higher OT/PT scores were observed in neurology and pulmonary categories (all p values < .05). Four oral and 6 pharyngeal domain components significantly differed across medical categories: tongue control during bolus hold (all p values < .04). Conclusions: The results of this feasibility study demonstrate that summative scores of swallowing physiology alone are not sufficiently robust to distinguish subtypes of dysphagia in broad, heterogeneous medical categories. Using OT/PT as subtypes only separated gastroenterology from the other categories, suggesting overlap in OT/PT scores between the latter categories.

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Year:  2018        PMID: 29800022      PMCID: PMC6195027          DOI: 10.1044/2018_AJSLP-17-0173

Source DB:  PubMed          Journal:  Am J Speech Lang Pathol        ISSN: 1058-0360            Impact factor:   2.408


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