Literature DB >> 29798943

Colorectal cancer: A looming threat, opportunities, and challenges for the Saudi population and its healthcare system.

Mohammad Azhar Aziz1, Haafiz Allah-Bakhsh2.   

Abstract

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Year:  2018        PMID: 29798943      PMCID: PMC5985640          DOI: 10.4103/sjg.SJG_164_18

Source DB:  PubMed          Journal:  Saudi J Gastroenterol        ISSN: 1319-3767            Impact factor:   2.485


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Global colorectal cancer (CRC) is projected to increase by 60% as early as 2030 which translates into 2.2 million new CRC cases and 1.1 million deaths.[1] Whereas these statistics indicate looming challenges, unprecedented opportunities enabling early diagnosis and a cure are also rapidly becoming part of clinical practice. CRC-related statistics are alarming for the Kingdom of Saudi Arabia. Saudi Cancer Registry data reveal CRC to be the second most common cancer across the population.[23] Despite this scenario, institution of CRC screening and early diagnosis remains a formidable challenge.[456] As a consequence, up to 24% of these patients have advanced disease with distant metastasis at initial diagnosis.[2] The disconnect between the magnitude of the problem and the necessary national action plan is obvious. Efforts to fill this gap include the empowerment of the primary healthcare system while being cognizant of the younger age population polarity of this nation. Indeed CRC “age-shift” to younger populations is now well recognized, as has been reported from the United States of America.[7] Thus, an inclusive and well-orchestrated program is essential to address this looming threat on a national front. An elegant discussion making the case for a national screening policy for CRC in the Kingdom was recently published.[8] Indeed only through implementation of such a policy, early CRC diagnosis and a cure can be envisioned as a population healthcare target. Such an initiative can be launched as a test and a tool to transform Saudi national healthcare delivery system for high-impact diseases. This discussion is timely because our healthcare delivery system is going through transformative changes with due emphasis on primary healthcare services – an element that has been slow to be established. Unfortunately, despite its one-of-a-kind tertiary healthcare system, the full potential of the allocated fiscal resources has not been harnessed largely due to poor integration of primary and tertiary care services. Without such a cohesion of primary and tertiary care services, an upswing in early age CRC could have a considerable negative impact on the economy in the long run. Therefore, it is high time that related healthcare disciplines such as gastroenterology, and medical and surgical oncology partner with the Saudi healthcare authorities in establishing a comprehensive national program aimed at early detection and treatment of CRC. Indeed, the stage is set for an encompassing and integrative CRC national program of excellence to prospectively tackle a looming national challenge through the application of molecular technologies enabling early diagnosis and curative therapies.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.
  8 in total

1.  Colorectal Cancer Incidence Patterns in the United States, 1974-2013.

Authors:  Rebecca L Siegel; Stacey A Fedewa; William F Anderson; Kimberly D Miller; Jiemin Ma; Philip S Rosenberg; Ahmedin Jemal
Journal:  J Natl Cancer Inst       Date:  2017-08-01       Impact factor: 13.506

2.  Colorectal cancer in the Kingdom of Saudi Arabia: need for screening.

Authors:  Mahmoud H Mosli; Mahmoud S Al-Ahwal
Journal:  Asian Pac J Cancer Prev       Date:  2012

3.  Global patterns and trends in colorectal cancer incidence and mortality.

Authors:  Melina Arnold; Mónica S Sierra; Mathieu Laversanne; Isabelle Soerjomataram; Ahmedin Jemal; Freddie Bray
Journal:  Gut       Date:  2016-01-27       Impact factor: 23.059

4.  Colon Cancer among Older Saudis: Awareness of Risk Factors and Early Signs, and Perceived Barriers to Screening.

Authors:  Yasmine Samir Galal; Tarek Tawfik Amin; Abdulelah Khalid Alarfaj; Abdulaziz Abdullah Almulhim; Abdullah Abdulmohsen Aljughaiman; Abdulrhaman Khaled Almulla; Rehab Ahmed Abdelhai
Journal:  Asian Pac J Cancer Prev       Date:  2016

5.  Knowledge, attitude, and practices of primary health care physicians toward colorectal cancer screening.

Authors:  Mahmoud Mosli; Yaser Alnahdi; Abdusalam Alghamdi; Mohammad Baabdullah; Afnan Hadadi; Khaleel Khateery; Ibrahim Alsulami; Abdulaziz AlHoqail; Majid Almadi; Hani Jawa; Emad Aljahdli; Salem Bazarah; Yousif Qari
Journal:  Saudi J Gastroenterol       Date:  2017 Nov-Dec       Impact factor: 2.485

6.  Cancer Incidence in Saudi Arabia: 2012 Data from the Saudi Cancer Registry

Authors:  Shouki Bazarbashi; Haya Al Eid; Joan Minguet
Journal:  Asian Pac J Cancer Prev       Date:  2017-09-27

7.  Policy of screening for colorectal cancer in Saudi Arabia: A prospective analysis.

Authors:  Abdulrahman A Aljumah; Abdulrahman M Aljebreen
Journal:  Saudi J Gastroenterol       Date:  2017 May-Jun       Impact factor: 2.485

8.  Initial guidelines for colorectal cancer screening in Saudi Arabia: a beginning.

Authors:  Majid A Almadi; Alan N Barkun
Journal:  Ann Saudi Med       Date:  2015 Sep-Oct       Impact factor: 1.526

  8 in total
  4 in total

Review 1.  Colorectal cancer in Saudi Arabia as the proof-of-principle model for implementing strategies of predictive, preventive, and personalized medicine in healthcare.

Authors:  Mesnad Alyabsi; Abdulrahman Alhumaid; Haafiz Allah-Bakhsh; Mohammed Alkelya; Mohammad Azhar Aziz
Journal:  EPMA J       Date:  2019-08-31       Impact factor: 6.543

2.  The gap between knowledge and undergoing colorectal cancer screening using the Health Belief Model: A national survey.

Authors:  Majid A Almadi; Faisal Alghamdi
Journal:  Saudi J Gastroenterol       Date:  2019 Jan-Feb       Impact factor: 2.485

3.  Serum vitamin D receptor (VDR) levels as a potential diagnostic marker for colorectal cancer.

Authors:  Ayat B Al-Ghafari; Khadijah S Balamash; Huda A Al Doghaither
Journal:  Saudi J Biol Sci       Date:  2020-01-21       Impact factor: 4.219

4.  Clinicopathological Characteristics and Overall 5-Year Survival of Colorectal Cancer: A Retrospective Study.

Authors:  Rahaf Almuhanna; Fatma Al-Thoubaity; Khadijah Almalki; Nada Algarni; Renad Hamad; Toleen Makhtoum
Journal:  Med Sci (Basel)       Date:  2022-08-09
  4 in total

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