Literature DB >> 29798667

Total Synthesis of the Highly N-Methylated Peptide Jahanyne.

Baijun Ye1, Peng Jiang1, Tingrong Zhang1, Yahui Ding1, Yuanjun Sun1, Xin Hao1, Lanshu Li1, Liang Wang1, Yue Chen1.   

Abstract

Total synthesis of jahanyne (1) was achieved from commercially available materials on a 38 mg scale. The Boc- N-Me- L-Val-OH fragment along with the HATU/DIPEA coupling condition was applied to avoid the diketopiperazine side reaction in solution phase synthesis.

Entities:  

Mesh:

Substances:

Year:  2018        PMID: 29798667     DOI: 10.1021/acs.joc.8b00503

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  3 in total

1.  Concise Chemoenzymatic Total Synthesis and Identification of Cellular Targets of Cepafungin I.

Authors:  Alexander Amatuni; Anton Shuster; Alexander Adibekian; Hans Renata
Journal:  Cell Chem Biol       Date:  2020-08-06       Impact factor: 8.116

2.  Total Synthesis of the Highly N-Methylated Peptides Carmabin A and Dragomabin.

Authors:  Baijun Ye; Peng Jiang; Tingrong Zhang; Yuanjun Sun; Xin Hao; Yingjun Cui; Liang Wang; Yue Chen
Journal:  Mar Drugs       Date:  2018-09-17       Impact factor: 5.118

3.  Design, Synthesis and Biological Evaluation of Jahanyne Analogs as Cell Cycle Arrest Inducers.

Authors:  Baijun Ye; Jianmiao Gong; Qiuying Li; Shiqi Bao; Xuemei Zhang; Jing Chen; Qing Meng; Bolin Chen; Peng Jiang; Liang Wang; Yue Chen
Journal:  Mar Drugs       Date:  2020-03-23       Impact factor: 5.118

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.