| Literature DB >> 29797251 |
Tina Smets1, Frederik Stevenaert1, Homer Adams2, Greet Vanhoof3.
Abstract
Mass cytometry has emerged as a new state-of-the-art technology that enables in-depth characterization of cellular populations and functions at a single cell resolution. We describe the application of this technology to deeply phenotype the blood and bone marrow components of multiple myeloma patients in a clinical setting. This technology allows for simultaneous quantification of more than 40 markers, overcoming the challenges of traditional fluorescence-based flow cytometry.Entities:
Keywords: Barcoding; Bone marrow; CyTOF; Immunophenotyping; Mass cytometry; Multiple myeloma; Peripheral blood; Single cell; Smart tube
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Year: 2018 PMID: 29797251 DOI: 10.1007/978-1-4939-7865-6_4
Source DB: PubMed Journal: Methods Mol Biol ISSN: 1064-3745