| Literature DB >> 29795365 |
William S Yancy1,2,3, Pamela A Shaw4,5, Lisa Wesby5,6,7, Victoria Hilbert5,8, Lin Yang9, Jingsan Zhu5,8, Andrea Troxel10, David Huffman5,11, Gary D Foster12,13,14, Alexis C Wojtanowski12, Kevin G Volpp5,6,8,9,15.
Abstract
BACKGROUND/Entities:
Mesh:
Year: 2018 PMID: 29795365 PMCID: PMC5968035 DOI: 10.1038/s41387-018-0036-y
Source DB: PubMed Journal: Nutr Diabetes ISSN: 2044-4052 Impact factor: 5.097
Fig. 1Flow of study participants
Baseline characteristics of study participants overall and by arm
| Characteristic | Total | Lottery | Direct payment | Control |
|---|---|---|---|---|
| Age, mean (SD) | 49.0 (10.5) | 48.8 (10.3) | 48.6 (11.0) | 50.1 (10.0) |
| Female gender, | 175 (91.6) | 70 (90.9) | 69 (92.0) | 36 (92.3) |
| Race, | ||||
| White | 170 (89.0) | 68 (88.3) | 69 (92.0) | 33 (84.6) |
| Black | 8 (4.2) | 3 (3.9) | 4 (5.3) | 1 (2.6) |
| Other | 6 (3.1) | 3 (3.9) | 1 (1.3) | 2 (5.1) |
| Two or more races | 7 (3.7) | 3 (3.9) | 1 (1.3) | 3 (7.7) |
| Hispanic, | 8 (4.2) | 2 (2.6) | 4 (5.3) | 2 (5.1) |
| Education, | ||||
| Less than college | 72 (37.7) | 26 (33.8) | 35 (46.7) | 11 (28.2) |
| College graduate | 55 (28.8) | 28 (36.4) | 11 (14.7) | 16 (41.0) |
| Post-college degree | 64 (33.5) | 23 (29.9) | 29 (38.7) | 12 (30.8) |
| Household income, | ||||
| <US$50,000 | 23 (12.0) | 12 (15.6) | 5 (6.7) | 6 (15.4) |
| US$50,000 to <US$100,000 | 96 (50.3) | 36 (46.8) | 40 (53.3) | 20 (51.3) |
| ≥US$100,000 | 72 (37.7) | 29 (37.7) | 30 (40.0) | 13 (33.3) |
| People per household, mean (SD) | 3.1 (1.4) | 3.2 (1.5) | 3.0 (1.4) | 3.0 (1.2) |
| Weight measures, mean (SD) | ||||
| Weight at the start of Weight Watchers | 101.6 (15.7) | 100.8 (15.7) | 101.7 (16.0) | 102.9 (15.6) |
| Weight at randomization | 90.2 (14.9) | 89.2 (14.3) | 90.7 (15.7) | 91.2 (15.0) |
| Weight loss prior to randomization | 11.4 (4.7) | 11.6 (4.4) | 10.9 (5.1) | 11.7 (4.3) |
| BMI measures | ||||
| BMI at start of Weight Watchers, mean (SD) | 36.7 (4.3) | 36.5 (4.4) | 36.8 (4.1) | 36.9 (4.5) |
| BMI at randomization, mean (SD) | 32.5 (4.1) | 32.3 (4.1) | 32.8 (4.3) | 32.6 (4.1) |
| BMI ≥35 kg/m2 at randomization, | 69 (36.1) | 26 (33.8) | 29 (38.7) | 14 (35.9) |
| Eating behaviors by TFEQ, mean (SD)a | ||||
| Cognitive restraint scale | 62.3 (14.4) | 62.0 (15.0) | 62.6 (14.6) | 62.4 (12.8) |
| Uncontrolled eating scale | 45.1 (16.0) | 44.4 (15.6) | 47.6 (16.2) | 41.8 (16.1) |
| Emotional eating scale | 59.9 (24.5) | 58.7 (23.8) | 63.3 (23.5) | 55.8 (27.2) |
| Physical activity in min per weekb, median (IQR) | ||||
| Moderate-vigorous activity min per week | 333 (120, 700) | 345 (180, 885) | 240 (60, 585) | 390 (180, 630) |
| Walking min per week | 148 (45, 428) | 180 (53, 537.5) | 100 (20, 360) | 150 (90, 325) |
| Total activity min per week | 510 (238, 1148) | 533 (283, 1295) | 460 (150, 990) | 600 (270, 925) |
a TFEQ Three-Factor Eating Questionnaire. The raw eating scale scores are transformed to a 0–100 scale [((raw score − lowest possible raw score)/possible raw score range) × 100] Higher scores in the respective scales are indicative of greater cognitive restraint, uncontrolled, or emotional eating
b Measured using the International Physical Activity Questionnaire. Data were missing for three participants: Lottery (n = 1), Direct (n = 2)
Fig. 2Average number of days per week self-weighing was performed by arm over time (randomization is time 0)
Fig. 3Percent weight change by arm from entry into Weight Watchers program over time (randomization is time 0)
Imputed change in weight, physical activity, and eating behaviors at 6 and 12 months by arm
| Lottery ( | Direct payment ( | Control ( | Lottery versus control | Direct payment versus control | Lottery versus direct payment | |
|---|---|---|---|---|---|---|
| Imputed weight change (kg)a | ||||||
| 6-month imputed weight change, mean (SD) | −3.0 (5.8) | −2.8 (5.8) | −1.4 (5.8) | −1.6 | −1.4 | −0.2 |
| 95% CI | −3.8, 0.6 | −3.7, 0.8 | −2.0, 1.7 | |||
| | 0.154 | 0.215 | 0.859 | |||
| 12-month imputed weight change, mean (SD) | −1.8 (10.5) | −0.7 (10.7) | −0.2 (9.4) | −1.6 | −0.5 | −1.1 |
| 95% CI | −5.3, 2.2 | −4.3, 3.4 | −4.3, 2.1 | |||
| | 0.408 | 0.813 | 0.494 | |||
| Moderate-vigorous activity min per week | ||||||
| 6-month change, mean (SD) | 50.5 (631.9) | −27.9 (529.3) | 270.8 (610.6) | −220.4 | −298.8 | 78.4 |
| 95% CI | −535.2, 94.5 | −624.7, 27.2 | −166.9, 323.7 | |||
| | 0.168 | 0.072 | 0.528 | |||
| 12-month change, mean (SD) | −15.2 (600.3) | 89.6 (376.3) | 101.3 (414.1) | −116.4 | −11.7 | −104.7 |
| 95% CI | −409.7, 176.9 | −298.0, 274.6 | −338.2, 128.7 | |||
| | 0.432 | 0.936 | 0.375 | |||
| Walking min per week | ||||||
| 6-month change, mean (SD) | 122.3 (492.2) | 23.5 (445.5) | −18.7 (295.0) | 141 | 42.2 | 98.7 |
| 95% CI | −96.6, 378.5 | −204.3, 288.8 | −86.0, 283.5 | |||
| | 0.242 | 0.735 | 0.292 | |||
| 12-month change, mean (SD) | −0.2 (540.2) | 68.3 (236.0) | 127.2 (459.2) | −127.3 | −58.9 | −68.5 |
| 95% CI | −382.4, 127.7 | −307.8, 190.1 | −271.5, 134.5 | |||
| | 0.323 | 0.639 | 0.504 | |||
| Total activity min per week | ||||||
| 6-month change, mean (SD) | 171.0 (908.2) | −4.4 (793.7) | 252.2 (776.8) | −81.2 | −256.5 | 175.4 |
| 95% CI | −530.1, 367.7 | −722.5, 209.4 | −173.8, 524.5 | |||
| | 0.721 | 0.278 | 0.322 | |||
| 12-month change, mean (SD) | −15.3 (932.0) | 157.9 (435.1) | 228.4 (670.2) | −243.8 | −70.5 | −173.2 |
| 95% CI | −673.8, 186.3 | −490.3, 349.2 | −515.5, 169.1 | |||
| | 0.263 | 0.739 | 0.317 | |||
| Cognitive restraint scale, TFEQ | ||||||
| 6-month scale change, mean (SD) | 1.5 (17.4) | 3.6 (12.2) | 3.2 (18.2) | −1.8 | 0.4 | −2.2 |
| 95% CI | −10.1, 6.6 | −8.2, 9.0 | −8.6, 4.3 | |||
| | 0.679 | 0.927 | 0.508 | |||
| 12-month scale change, mean (SD) | −2.0 (17.9) | −2.2 (16.2) | 2.8 (16.9) | −4.8 | −4.9 | 0.1 |
| 95% CI | −15.1, 5.5 | −15.1, 5.2 | −8.0, 8.3 | |||
| | 0.358 | 0.337 | 0.973 | |||
| Uncontrolled eating scale, TFEQ | ||||||
| 6-month scale change, mean (SD) | −3.5 (13.8) | 0.3 (16.1) | −2.1 (15.7) | −1.4 | 2.4 | −3.8 |
| 95% CI | −9.3, 6.6 | −5.8, 10.6 | −9.9, 2.4 | |||
| | 0.738 | 0.563 | 0.226 | |||
| 12-month scale change, mean (SD) | −3.7 (15.6) | 0.5 (11.9) | −3.2 (14.9) | −0.5 | 3.8 | −4.2 |
| 95% CI | −8.9, 8.0 | −4.6, 12.1 | −10.9, 2.5 | |||
| | 0.914 | 0.374 | 0.214 | |||
| Emotional eating scale, TFEQ | ||||||
| 6-month scale change, mean (SD) | −6.7 (16.5) | −1.3 (18.2) | −4.7 (16.3) | −2.0 | 3.4 | −5.4 |
| 95% CI | −11.1, 7.0 | −6.0, 12.7 | −12.4, 1.5 | |||
| | 0.658 | 0.474 | 0.126 | |||
| 12-month scale change, mean (SD) | −4.4 (19.4) | 0.0 (14.8) | 3.5 (15.0) | −7.9 | −3.5 | −4.4 |
| 95% CI | −18.0, 2.3 | −13.5, 6.6 | −12.4, 3.7 | |||
| | 0.129 | 0.493 | 0.283 | |||
TFEQ Three-Factor Eating Questionnaire. The raw eating scale scores are transformed to a 0–100 scale [((raw score − lowest possible raw score)/possible raw score range) × 100] Higher scores in the respective scales are indicative of greater cognitive restraint, uncontrolled, or emotional eating
aWeight change (primary outcome) models were adjusted for the baseline factors age, sex, race, education, income, weight, WW program starting BMI, and qualifying weight loss