Literature DB >> 29794244

Cardiac auscultation poorly predicts the presence of valvular heart disease in asymptomatic primary care patients.

Syed K M Gardezi1,2, Saul G Myerson1,2, John Chambers3, Sean Coffey4, Joanna d'Arcy1, F D Richard Hobbs5, Jonathan Holt6, Andrew Kennedy1, Margaret Loudon1, Anne Prendergast7, Anthony Prothero1, Joanna Wilson1, Bernard D Prendergast3.   

Abstract

OBJECTIVE: Cardiac auscultation is a key clinical skill, particularly for the diagnosis of valvular heart disease (VHD). However, its utility has declined due to the widespread availability of echocardiography and diminishing emphasis on the importance of clinical examination. We aim to determine the contemporary accuracy of auscultation for diagnosing VHD in primary care.
METHODS: Cardiac auscultation was undertaken by one of two experienced general practitioners (primary care/family doctors) in a subset of 251 asymptomatic participants aged >65 years undergoing echocardiography within a large community-based screening study of subjects with no known VHD. Investigators were blinded to the echocardiographic findings. Newly detected VHD was classified as mild (mild regurgitation of any valve or aortic sclerosis) or significant (at least moderate regurgitation or mild stenosis of any valve).
RESULTS: Newly identified VHD was common, with mild disease in 170/251 participants (68%) and significant disease in 36/251 (14%). The sensitivity of auscultation was low for the diagnosis of mild VHD (32%) but slightly higher for significant VHD (44%), with specificities of 67% and 69%, respectively. Likelihood ratios were not statistically significant for the diagnosis of either mild or significant VHD in the overall cohort, but showed possible value for auscultation in non-overweight subjects (body mass index <25 kg/m2).
CONCLUSION: Cardiac auscultation has limited accuracy for the detection of VHD in asymptomatic patients and is a poor diagnostic screening tool in primary care, particularly for overweight subjects. Ensuring easy access to echocardiography in patients with symptoms suggesting VHD is likely to represent a better diagnostic strategy. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Entities:  

Keywords:  health care economics; primary care; quality and outcomes of care; valvular heart disease

Mesh:

Year:  2018        PMID: 29794244     DOI: 10.1136/heartjnl-2018-313082

Source DB:  PubMed          Journal:  Heart        ISSN: 1355-6037            Impact factor:   5.994


  12 in total

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Review 3.  Valvular Heart Disease Epidemiology.

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4.  S2 Heart Sound Detects Aortic Valve Calcification Independent of Hemodynamic Changes in Mice.

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5.  Priorities for Patient-Centered Research in Valvular Heart Disease: A Report From the National Heart, Lung, and Blood Institute Working Group.

Authors:  Brian R Lindman; Suzanne V Arnold; Rodrigo Bagur; Lindsay Clarke; Megan Coylewright; Frank Evans; Judy Hung; Sandra B Lauck; Susan Peschin; Vandana Sachdev; Lisa M Tate; Jason H Wasfy; Catherine M Otto
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Review 6.  EDUCATIONAL SERIES ON THE SPECIALIST VALVE CLINIC: How to run a specialist valve clinic: the history, examination and exercise test.

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7.  Multiple biomarker panel to screen for severe aortic stenosis: results from the CASABLANCA study.

Authors:  Sammy Elmariah; Cian McCarthy; Nasrien Ibrahim; Deborah Furman; Renata Mukai; Craig Magaret; Rhonda Rhyne; Grady Barnes; Roland R J van Kimmenade; James L Januzzi
Journal:  Open Heart       Date:  2018-11-01

8.  Murmur clinic: validation of a new model for detecting heart valve disease.

Authors:  Jane Draper; Sheila Subbiah; Rikki Bailey; John B Chambers
Journal:  Heart       Date:  2018-07-26       Impact factor: 5.994

Review 9.  Imaging assessment of mitral and aortic regurgitation: current state of the art.

Authors:  Richard Paul Steeds; Saul G Myerson
Journal:  Heart       Date:  2020-08-17       Impact factor: 5.994

Review 10.  Global epidemiology of valvular heart disease.

Authors:  Sean Coffey; Ross Roberts-Thomson; Alex Brown; Jonathan Carapetis; Mao Chen; Maurice Enriquez-Sarano; Liesl Zühlke; Bernard D Prendergast
Journal:  Nat Rev Cardiol       Date:  2021-06-25       Impact factor: 32.419

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