Literature DB >> 29793257

A critical view of the general public's awareness and physicians' opinion of the trends and potential pitfalls of genetic testing in Greece.

Yuan Mai1, Theodora Koromila2, Aggeliki Sagia1, David N Cooper3, Georgios Vlachopoulos4, George Lagoumintzis5, Panagoula Kollia2, Konstantinos Poulas1, Vlassios Stathakopoulos6, George P Patrinos7.   

Abstract

AIM: Progress in deciphering the functionality of the human genome sequence in the wake of technological advances in the field of genomic medicine have dramatically reduced the overall costs of genetic analysis, thereby facilitating the incorporation of genetic testing services into mainstream clinical practice. Although Greek genetic testing laboratories offer a variety of different genetic tests, relatively little is known about how either the general public or medical practitioners perceive genetic testing services. MATERIALS &
METHODS: We have therefore performed a nationwide survey of the views of 1717 members of the general public, divided into three age groups, from all over Greece, and residing in both large and small cities and villages, in order to acquire a better understanding of how they perceive genetic testing. We also canvassed the opinions of 496 medical practitioners with regard to genetic testing services in a separate survey that addressed similar issues.
RESULTS: Our subsequent analysis indicated that a large proportion of the general public is aware of the nature of DNA, genetic disorders and the potential benefits of genetic testing, although this proportion declines steadily with age. Furthermore, a large proportion of the interviewed individuals would be willing to undergo genetic testing even if the cost of analysis was not covered by healthcare insurance. However, a relatively small proportion of the general public has actually been advized to undergo genetic testing, either by relatives or physicians. Most physicians believe that the regulatory and legal framework that governs genetic testing services in Greece is rather weak. Interestingly, the vast majority of the general public strongly opposes direct-access genetic testing, and most would prefer referral from a physician than from a pharmacist.
CONCLUSION: Overall, our results provide a critical evaluation of the views of the general public with regard to genetics and genetic testing services in Greece and should serve as a model for replication in other populations.

Entities:  

Keywords:  education; general public awareness; genetic testing; healthcare; insurance cost; molecular genetics; pharmacogenomics; physicians’ opinion; reimbursement

Year:  2011        PMID: 29793257     DOI: 10.2217/pme.11.48

Source DB:  PubMed          Journal:  Per Med        ISSN: 1741-0541            Impact factor:   2.512


  7 in total

1.  Institutional Profile: Golden Helix Institute of Biomedical Research: interdisciplinary research and educational activities in pharmacogenomics and personalized medicine.

Authors:  Konstantinos Mitropoulos; Federico Innocenti; Ron H van Schaik; Alexander Lezhava; Giannis Tzimas; Panagoula Kollia; Milan Macek; Paolo Fortina; George P Patrinos
Journal:  Pharmacogenomics       Date:  2012-03       Impact factor: 2.533

2.  Atti Le giornate della ricerca scientificae delle esperienze professionali dei giovani: Società Italiana di Igiene, Medicina Preventiva e Sanità Pubblica (SItI) Roma 20-21 dicembre 2019.

Authors: 
Journal:  J Prev Med Hyg       Date:  2020-02-13

3.  Roadmap for Establishing Large-Scale Genomic Medicine Initiatives in Low- and Middle-Income Countries.

Authors:  George P Patrinos; Emmanouil Pasparakis; Erasmia Koiliari; Alexandre C Pereira; Tábita Hünemeier; Lygia V Pereira; Christina Mitropoulou
Journal:  Am J Hum Genet       Date:  2020-10-01       Impact factor: 11.025

4.  Clinical pharmacogenomics: patient perspectives of pharmacogenomic testing and the incidence of actionable test results in a chronic disease cohort.

Authors:  Chandrama Mukherjee; Kevin M Sweet; Jasmine A Luzum; Mahmoud Abdel-Rasoul; Michael F Christman; Joseph P Kitzmiller
Journal:  Per Med       Date:  2017-09-01       Impact factor: 2.512

5.  Modeling factors critical for implementation of precision medicine at health systems-level: an IRT approach.

Authors:  John Jo Mogaka; Moses J Chimbari
Journal:  Am J Transl Res       Date:  2021-11-15       Impact factor: 4.060

6.  Genetic Testing Consumers in Italy: A Preliminary Investigation of the Socio-Demographic Profile, Health-Related Habits, and Decision Purposes.

Authors:  Serena Oliveri; Giulia Marton; Laura Vergani; Ilaria Cutica; Alessandra Gorini; Francesca Spinella; Gabriella Pravettoni
Journal:  Front Public Health       Date:  2020-10-08

7.  Citizens' Attitudes, Knowledge, and Educational Needs in the Field of Omics Sciences: A Systematic Literature Review.

Authors:  Giovanna Elisa Calabrò; Michele Sassano; Alessia Tognetto; Stefania Boccia
Journal:  Front Genet       Date:  2020-10-23       Impact factor: 4.599

  7 in total

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