Literature DB >> 29792272

Facing cinacalcet-induced hypocalcemia: sit back and relax?

Pieter Evenepoel1, Rukshana Shroff2.   

Abstract

A post hoc analysis of data from the EVOLVE study demonstrates that cinacalcet-induced hypocalcemia is common, mostly asymptomatic, and resolves spontaneously. These findings are reassuring and may warrant therapeutic inertia. However, previous studies in parathyroidectomized patients suggest that calcium repletion may be beneficial and safe from bone and cardiovascular perspectives, respectively, and as such call into question the appropriateness of a "sit back and relax" attitude toward cinacalcet-induced hypocalcemia.
Copyright © 2018 International Society of Nephrology. Published by Elsevier Inc. All rights reserved.

Entities:  

Mesh：

Substances：

Year:  2018        PMID： 29792272     DOI： 10.1016/j.kint.2018.01.038

Source DB:  PubMed          Journal:  Kidney Int        ISSN： 0085-2538            Impact factor:   10.612


  4 in total

1.  Cinacalcet-induced hypocalcemia in a cohort of European haemodialysis patients: predictors, therapeutic approaches and outcomes.

Authors:  Karly S Louie; Clement Erhard; David C Wheeler; Peter Stenvinkel; Bruno Fouqueray; Jürgen Floege
Journal:  J Nephrol       Date:  2019-12-17       Impact factor: 3.902

2.  The impact of cinacalcet in the mineral metabolism markers of patients on dialysis with severe secondary hyperparathyroidism.

Authors:  Sérgio Gardano Elias Bucharles; Fellype Carvalho Barreto; Miguel Carlos Riella
Journal:  J Bras Nefrol       Date:  2019-07-18

Review 3.  The dietary management of calcium and phosphate in children with CKD stages 2-5 and on dialysis-clinical practice recommendation from the Pediatric Renal Nutrition Taskforce.

Authors:  Louise McAlister; Pearl Pugh; Laurence Greenbaum; Dieter Haffner; Lesley Rees; Caroline Anderson; An Desloovere; Christina Nelms; Michiel Oosterveld; Fabio Paglialonga; Nonnie Polderman; Leila Qizalbash; José Renken-Terhaerdt; Jetta Tuokkola; Bradley Warady; Johan Vande Walle; Vanessa Shaw; Rukshana Shroff
Journal:  Pediatr Nephrol       Date:  2019-10-30       Impact factor: 3.714

4.  Pharmacogenetic and safety analysis of cinacalcet hydrochloride in healthy Chinese subjects.

Authors:  Yang-Jie Liu; Lu-Ning Sun; Zi-Ping Cheng; Yi Qian; Zeng-Qing Ma; Xue-Hui Zhang; Hong-Wen Zhang; Li-Jun Xie; Lei Yu; Zi-Qing-Yun Yuan; Yun Liu; Yong-Qing Wang
Journal:  Ann Transl Med       Date:  2020-11
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.