Literature DB >> 29792268

Toward individual glomerular phenotyping: advent of precision medicine in kidney biopsies.

Kumar Sharma1, Ljiljana Paša-Tolić2.   

Abstract

The road to precision medicine for nephrology is approaching quickly. In the present volume, the glomerular proteome has now been characterized at a single glomerulus level in mouse and human kidneys. Using the Single-Pot Solid-Phase-enhanced Sample Preparation (SP3) approach the authors demonstrated that LAMP1 is a key lysosomal protein that is increased in glomerular diseases and may play a pathogenic role.
Copyright © 2018 International Society of Nephrology. Published by Elsevier Inc. All rights reserved.

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Year:  2018        PMID: 29792268      PMCID: PMC6583000          DOI: 10.1016/j.kint.2018.01.035

Source DB:  PubMed          Journal:  Kidney Int        ISSN: 0085-2538            Impact factor:   10.612


  1 in total

1.  Heterogenous Renal Injury Biomarker Production Reveals Human Sepsis-Associated Acute Kidney Injury Subtypes.

Authors:  Daniela Jou-Valencia; Jacqueline Koeze; Eliane R Popa; Adnan Aslan; Peter J Zwiers; Grietje Molema; Jan G Zijlstra; Matijs van Meurs; Jill Moser
Journal:  Crit Care Explor       Date:  2019-10-14
  1 in total

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