Literature DB >> 29789053

Management of Meconium-Stained Newborns in the Delivery Room.

Chintan Kiritkumar Gandhi.   

Abstract

The approach to the management of meconium-stained newborns in the delivery room has been changing for over 40 years. The goal is to prevent meconium aspiration syndrome (MAS) and complications related to MAS. For decades, airway obstruction was believed to be a major component of MAS and, consequently, suction maneuvers to remove meconium from the airways were recommended to decrease the frequency and severity of MAS. Initial recommendations were based on observational studies. However, the incidence of MAS and mortality related to MAS has declined since the 1970s, mostly because of a decrease in the number of postterm deliveries. Recently updated guidelines by the American Heart Association and the Neonatal Resuscitation Program have reflected the strength of evidence supporting tracheal intubation and suctioning for nonvigorous, meconium-stained newborns. This article examines practice change since the 1970s in the delivery room management of meconium-stained newborns and evaluates evidence behind the changes.

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Year:  2018        PMID: 29789053     DOI: 10.1891/0730-0832.37.3.141

Source DB:  PubMed          Journal:  Neonatal Netw        ISSN: 0730-0832


  4 in total

1.  A retrospective cohort study of tracheal intubation for meconium suction in nonvigorous neonates.

Authors:  Kai-Li Li; Cheng-He Tang
Journal:  Zhongguo Dang Dai Er Ke Za Zhi       Date:  2022-01-15

Review 2.  The Efficacy of CPAP in Neonates with Meconium Aspiration Syndrome: A Systematic Review and Meta-Analysis.

Authors:  Carlos J Toro-Huamanchumo; Maryori M Hilario-Gomez; Nelson Diaz-Reyes; José A Caballero-Alvarado; Joshuan J Barboza
Journal:  Children (Basel)       Date:  2022-04-21

3.  Degradation of Lung Protective Angiotensin Converting Enzyme-2 by Meconium in Human Alveolar Epithelial Cells: A Potential Pathogenic Mechanism in Meconium Aspiration Syndrome.

Authors:  Chintan K Gandhi; Romel Holmes; Ira H Gewolb; Bruce D Uhal
Journal:  Lung       Date:  2019-02-13       Impact factor: 2.584

Review 4.  Meconium Aspiration Syndrome: A Narrative Review.

Authors:  Chiara Monfredini; Francesco Cavallin; Paolo Ernesto Villani; Giuseppe Paterlini; Benedetta Allais; Daniele Trevisanuto
Journal:  Children (Basel)       Date:  2021-03-17
  4 in total

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