Da-Hye Son1, Ji-Won Yoo2, Mi-Ra Cho1, Yong-Jae Lee1,3. 1. Department of Family Medicine, Yonsei University College of Medicine, Seoul, Korea. 2. Devision of Geriatrics, Department of Internal Medicine, School of Medicine, University of Nevada Las Vegas, Nevada. 3. Department of Healthcare Administration and Policy, School of Community Health Sciences, University of Nevada, Las Vegas, Las Vegas, Nevada.
Abstract
OBJECTIVES: To investigate the relationship between handgrip strength and pulmonary function. DESIGN: Cross-sectional study of a representative sample of older Korean women. SETTING: The Korean National Health and Nutrition Examination Survey. PARTICIPANTS: Community-dwelling women aged 65 and older without chronic diseases or pulmonary disease (N=605). MEASUREMENTS: Handgrip strength was measured using a digital hand dynamometer, and pulmonary function was tested according to guidelines of the American Thoracic Society/European Respiratory Society using a spirometry system. Impaired pulmonary function was defined as a lower limit of normal (LLN) or less of forced vital capacity (FVC) and forced expiratory volume in 1 second (FEV1). Odds ratios (ORs) and 95% confidence intervals (CIs) for impaired pulmonary function according to handgrip strength quartile were calculated using multiple logistic regression analysis. RESULTS: Mean FVC and FEV1 gradually increased in accordance with handgrip strength quartiles (all P <.001). After adjusting for age, body mass index, smoking status, alcohol ingestion, aerobic physical activity, resistance exercise, household income, and education level the odds of impaired pulmonary function were greater for participants in the first quartile of handgrip strength (≤19.25 kg) than for those in the fourth quartile (25.31-37.30 kg) (FVC LLN: OR=3.46, 95 % CI=1.52-7.88; FEV1 LLN: OR=2.62, 95 % CI=1.12-6.15). CONCLUSION: Handgrip strength was positively associated with pulmonary function in a dose-dependent manner. Given the health implications of pulmonary function, timely detection of weaker handgrip strength in older people may be useful in assessing potential pulmonary function impairment.
OBJECTIVES: To investigate the relationship between handgrip strength and pulmonary function. DESIGN: Cross-sectional study of a representative sample of older Korean women. SETTING: The Korean National Health and Nutrition Examination Survey. PARTICIPANTS: Community-dwelling women aged 65 and older without chronic diseases or pulmonary disease (N=605). MEASUREMENTS: Handgrip strength was measured using a digital hand dynamometer, and pulmonary function was tested according to guidelines of the American Thoracic Society/European Respiratory Society using a spirometry system. Impaired pulmonary function was defined as a lower limit of normal (LLN) or less of forced vital capacity (FVC) and forced expiratory volume in 1 second (FEV1). Odds ratios (ORs) and 95% confidence intervals (CIs) for impaired pulmonary function according to handgrip strength quartile were calculated using multiple logistic regression analysis. RESULTS: Mean FVC and FEV1 gradually increased in accordance with handgrip strength quartiles (all P <.001). After adjusting for age, body mass index, smoking status, alcohol ingestion, aerobic physical activity, resistance exercise, household income, and education level the odds of impaired pulmonary function were greater for participants in the first quartile of handgrip strength (≤19.25 kg) than for those in the fourth quartile (25.31-37.30 kg) (FVC LLN: OR=3.46, 95 % CI=1.52-7.88; FEV1 LLN: OR=2.62, 95 % CI=1.12-6.15). CONCLUSION: Handgrip strength was positively associated with pulmonary function in a dose-dependent manner. Given the health implications of pulmonary function, timely detection of weaker handgrip strength in older people may be useful in assessing potential pulmonary function impairment.
Authors: Francesco Landi; Sara Salini; Maria Beatrice Zazzara; Anna Maria Martone; Sofia Fabrizi; Mariangela Bianchi; Matteo Tosato; Anna Picca; Riccardo Calvani; Emanuele Marzetti Journal: J Cachexia Sarcopenia Muscle Date: 2019-12-04 Impact factor: 12.910
Authors: Tam Ngoc Nguyen; Tu Ngoc Nguyen; Anh Trung Nguyen; Thanh Xuan Nguyen; Huong Thu Thi Nguyen; Thu Thi Hoai Nguyen; Thang Pham; Huyen Thanh Thi Vu Journal: BMJ Open Date: 2020-09-17 Impact factor: 2.692