| Literature DB >> 29784999 |
Stefania Camastra1, Alessandra Vitali2, Marco Anselmino3, Amalia Gastaldelli4, Rosario Bellini3, Rossana Berta3, Ilenia Severi2, Simona Baldi5, Brenno Astiarraga5, Giorgio Barbatelli2, Saverio Cinti2, Ele Ferrannini4.
Abstract
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Year: 2018 PMID: 29784999 PMCID: PMC5962565 DOI: 10.1038/s41598-018-25221-1
Source DB: PubMed Journal: Sci Rep ISSN: 2045-2322 Impact factor: 4.379
Correlation among clinical, histological, and metabolic parameters in the combined ND and T2D groups.
| BASELINE | BEFORE AND AFTER SURGERY | |||||||||||||||
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| Adipocyte area VAT | CLS VAT | Adipocyte area SAT | CLS SAT | Perivascular muscle fat | Interfibrillar muscle fat | Intramyocellular fat | Adipocyte mitochondria size | |||||||||
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| Adipocyte area SAT | 0.76 | <0.0001 | ns | — | — | 0.60 | <0.0001 | ns | 0.54 | 0.0001 | 0.57 | 0.0006 | −0.36 | 0.01 | ||
| CLS SAT | 0.59 | 0.008 | 0.61 | 0.006 | 0.60 | <0.0001 | — | — | ns | ns | 0.39 | 0.03 | ns | |||
| Perivasc. muscle fat | ns | 0.47 | 0.04 | ns | ns | — | — | 0.43 | 0.007 | ns | ns | |||||
| Interfibrill. muscle fat | ns | ns | 0.54 | 0.001 | ns | 0.43 | 0.007 | — | — | 0.50 | 0.003 | ns | ||||
| Intramyocellular fat | 0.60 | 0.005 | ns | 0.57 | 0.0006 | 0.39 | 0.03 | ns | 0.50 | 0.003 | — | — | ns | |||
| BMI | ns | ns | 0.89 | <0.0001 | 0.50 | 0.001 | ns | 0.45 | 0.004 | 0.42 | 0.008 | −0.61 | <0.0001 | |||
| Waist circumference | 0.59 | 0.01 | 0.54 | 0.03 | 0.86 | <0.0001 | 0.61 | 0.001 | 0.44 | 0.03 | 0.44 | 0.03 | ns | ns | −0.41 | 0.004 |
| Fasting glucose | ns | 0.60 | 0.002 | 0.44 | 0.003 | 0.36 | 0.04 | 0.36 | 0.04 | ns | 0.35 | 0.04 | ns | |||
| Fasting insulin | ns | ns | 0.70 | <0.0001 | 0.52 | 0.0008 | 0.46 | 0.004 | ns | 0.36 | 0.03 | −0.20 | 0.049 | |||
| HbA1c | ns | 0.65 | 0.02 | 0.54 | 0.02 | 0.57 | 0.02 | ns | ns | ns | ns | |||||
| Mean Glucose | 0.43 | 0.04 | 0.53 | 0.007 | 0.40 | 0.009 | 0.57 | 0.0003 | ns | 0.41 | 0.01 | ns | ns | |||
| Adiponectin | ns | ns | −0.56 | 0.0002 | −0.39 | 0.02 | ns | ns | ns | 0.54 | 0.0004 | |||||
| MCP1 | ns | ns | 0.35 | 0.03 | 0.37 | 0.03 | ns | ns | 0.40 | 0.02 | ns | |||||
| IL-6 | ns | ns | 0.50 | 0.001 | ns | 0.41 | 0.02 | ns | 0.40 | 0.02 | ns | |||||
| M | ns | −0.42 | 0.03 | −0.62 | <0.0001 | −0.42 | 0.009 | −0.35 | 0.03 | ns | ns | ns | ||||
| M/I | ns | ns | −0.72 | <0.0001 | −0.43 | 0.008 | −0.35 | 0.03 | −0.36 | 0.03 | ns | 0.38 | 0.004 | |||
| AT-IR | ns | ns | 0.58 | <0.0001 | 0.35 | 0.04 | 0.51 | 0.001 | ns | ns | ns | |||||
| ß-GS | −0.58 | 0.004 | −0.50 | 0.02 | ns | −0.43 | 0.01 | ns | ns | −0.48 | 0.004 | ns | ||||
| Fasting ISR | ns | ns | 0.54 | 0.0002 | 0.45 | 0.006 | 0.41 | 0.002 | ns | ns | ns | |||||