Literature DB >> 29784850

Molecular Analysis of a blaIMP-1-Harboring Class 3 Integron in Multidrug-Resistant Pseudomonas fulva.

Masaki Yamamoto1, Yasufumi Matsumura2, Ryota Gomi3, Tomonari Matsuda4, Satoshi Nakano2, Miki Nagao2, Michio Tanaka2, Satoshi Ichiyama2.   

Abstract

A multidrug-resistant (MDR) Pseudomonas fulva strain was isolated in 2006 from a urine sample. The isolate harbored the blaIMP-1 gene, which was located in a chromosomal Tn402-like class 3 integron as a gene cassette array of aacA31-fosE-blaIMP-1 Two mutations in gyrA and one mutation in parC were detected in quinolone-resistance-determining regions (QRDRs). We report a full-length, novel, blaIMP-1-carrying class 3 integron. This integron, together with mutations in QRDRs, could have influenced the MDR phenotype.
Copyright © 2018 American Society for Microbiology.

Entities:  

Keywords:  carbapenemase; class 3 integron; genetic environment; mechanisms of resistance; metallo-β-lactamases

Mesh:

Substances:

Year:  2018        PMID: 29784850      PMCID: PMC6105817          DOI: 10.1128/AAC.00701-18

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  21 in total

Review 1.  Carbapenem-Resistant Non-Glucose-Fermenting Gram-Negative Bacilli: the Missing Piece to the Puzzle.

Authors:  Thomas J Gniadek; Karen C Carroll; Patricia J Simner
Journal:  J Clin Microbiol       Date:  2016-02-24       Impact factor: 5.948

Review 2.  Metallo-β-lactamases: a last frontier for β-lactams?

Authors:  Giuseppe Cornaglia; Helen Giamarellou; Gian Maria Rossolini
Journal:  Lancet Infect Dis       Date:  2011-05       Impact factor: 25.071

3.  An antibiotic-resistant class 3 integron in an Enterobacter cloacae isolate from hospital effluent.

Authors:  O Barraud; M Casellas; C Dagot; M-C Ploy
Journal:  Clin Microbiol Infect       Date:  2013-03-04       Impact factor: 8.067

4.  PCR typing of genetic determinants for metallo-beta-lactamases and integrases carried by gram-negative bacteria isolated in Japan, with focus on the class 3 integron.

Authors:  Naohiro Shibata; Yohei Doi; Kunikazu Yamane; Tetsuya Yagi; Hiroshi Kurokawa; Keigo Shibayama; Haru Kato; Kumiko Kai; Yoshichika Arakawa
Journal:  J Clin Microbiol       Date:  2003-12       Impact factor: 5.948

5.  Detection of point mutations associated with antibiotic resistance in Pseudomonas aeruginosa.

Authors:  Neda Gorgani; Scott Ahlbrand; Andrew Patterson; Nader Pourmand
Journal:  Int J Antimicrob Agents       Date:  2009-08-04       Impact factor: 5.283

6.  A novel integron-like element carrying the metallo-beta-lactamase gene blaIMP.

Authors:  Y Arakawa; M Murakami; K Suzuki; H Ito; R Wacharotayankun; S Ohsuka; N Kato; M Ohta
Journal:  Antimicrob Agents Chemother       Date:  1995-07       Impact factor: 5.191

7.  Interspecies Dissemination of a Mobilizable Plasmid Harboring blaIMP-19 and the Possibility of Horizontal Gene Transfer in a Single Patient.

Authors:  Masaki Yamamoto; Yasufumi Matsumura; Ryota Gomi; Tomonari Matsuda; Michio Tanaka; Miki Nagao; Shunji Takakura; Shinji Uemoto; Satoshi Ichiyama
Journal:  Antimicrob Agents Chemother       Date:  2016-08-22       Impact factor: 5.191

8.  Unicycler: Resolving bacterial genome assemblies from short and long sequencing reads.

Authors:  Ryan R Wick; Louise M Judd; Claire L Gorrie; Kathryn E Holt
Journal:  PLoS Comput Biol       Date:  2017-06-08       Impact factor: 4.475

9.  Differentiation in quinolone resistance by virulence genotype in Pseudomonas aeruginosa.

Authors:  Melissa Agnello; Annie Wong-Beringer
Journal:  PLoS One       Date:  2012-08-08       Impact factor: 3.240

10.  An extensive evaluation of read trimming effects on Illumina NGS data analysis.

Authors:  Cristian Del Fabbro; Simone Scalabrin; Michele Morgante; Federico M Giorgi
Journal:  PLoS One       Date:  2013-12-23       Impact factor: 3.240

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  1 in total

Review 1.  Antibiotic Resistant Pseudomonas Spp. Spoilers in Fresh Dairy Products: An Underestimated Risk and the Control Strategies.

Authors:  Laura Quintieri; Francesca Fanelli; Leonardo Caputo
Journal:  Foods       Date:  2019-09-01
  1 in total

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