Literature DB >> 29784640

Hypoxia downregulates protein S expression.

Vijaya S Pilli1, Arani Datta1, Sadaf Afreen1, Donna Catalano2, Gyongyi Szabo2, Rinku Majumder1.   

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Year:  2018        PMID: 29784640      PMCID: PMC6071559          DOI: 10.1182/blood-2018-04-841585

Source DB:  PubMed          Journal:  Blood        ISSN: 0006-4971            Impact factor:   25.476


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2.  The Journey of Protein S from an Anticoagulant to a Signaling Molecule.

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4.  PHDs overactivation during chronic hypoxia "desensitizes" HIFalpha and protects cells from necrosis.

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5.  Ethanol and tobacco smoke increase hepatic steatosis and hypoxia in the hypercholesterolemic apoE(-/-) mouse: implications for a "multihit" hypothesis of fatty liver disease.

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6.  Acute alcohol produces hypoxia directly in rat liver tissue in vivo: role of Kupffer cells.

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Review 7.  Hypoxia-inducible factor 1 (HIF-1) pathway.

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8.  A case of hereditary protein S deficiency presenting with cerebral sinus venous thrombosis and deep vein thrombosis at high altitude.

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6.  COVID-19: a probable role of the anticoagulant Protein S in managing COVID-19-associated coagulopathy.

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Review 7.  Re-evaluation of hematocrit as a determinant of thrombotic risk in erythrocytosis.

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Review 8.  Protein S: function, regulation, and clinical perspectives.

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