Literature DB >> 29783451

Removing barriers to a clinical pharmacogenetics service.

William Newman1, Katherine Payne2.   

Abstract

Pharmacogenetics has been proposed as a new discipline to facilitate safer and more effective prescribing by predicting individuals who will have a therapeutic response or develop side effects. Implementation of pharmacogenetic testing into mainstream clinical practice has been slow. However, recent studies provide robust evidence that pharmacogenetics can make real differences to reduce adverse reactions to certain medications. It is therefore important to consider what factors influence the introduction of pharmacogenetics into clinical practice and what requirements must be met to ensure an effective, safe, efficient and equitable pharmacogenetics service.

Keywords:  clinical service; evidence level; guidelines; pharmacogenetics

Year:  2008        PMID: 29783451     DOI: 10.2217/17410541.5.5.471

Source DB:  PubMed          Journal:  Per Med        ISSN: 1741-0541            Impact factor:   2.512


  4 in total

Review 1.  The Routine Clinical use of Pharmacogenetic Tests: What it Will Require?

Authors:  Mafalda M Dias; Michael J Sorich; Andrew Rowland; Michael D Wiese; Ross A McKinnon
Journal:  Pharm Res       Date:  2017-02-24       Impact factor: 4.200

2.  Understanding barriers to the introduction of precision medicines in non-small cell lung cancer: A qualitative interview protocol.

Authors:  Stuart Wright; Gavin Daker-White; William Newman; Katherine Payne
Journal:  Wellcome Open Res       Date:  2018-03-08

3.  Accounting for Capacity Constraints in Economic Evaluations of Precision Medicine: A Systematic Review.

Authors:  Stuart J Wright; William G Newman; Katherine Payne
Journal:  Pharmacoeconomics       Date:  2019-08       Impact factor: 4.981

4.  Implementing Interventions with Varying Marginal Cost-Effectiveness: An Application in Precision Medicine.

Authors:  Stuart J Wright; Mike Paulden; Katherine Payne
Journal:  Med Decis Making       Date:  2020-10       Impact factor: 2.583

  4 in total

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