| Literature DB >> 29779108 |
V A Tarasov1, M G Tyutyakina2, M A Makhotkin1, E F Shin1, A V Naboka1, A N Mashkarina1, D A Chebotarev1, E N Cherkasova1, M I Kogan1,3, M B Chibichyan1,3, D G Matishov1.
Abstract
Using multiple parallel sequencing on Illumina platform, we identified eight microRNAs that showed significant opposite changes of gene expression in cells of the hormone-sensitive LNCaP prostate cancer cell line and in cells of the hormone-resistant DU-145 cell line, in comparison to the microRNA expression in the normal prostate tissue cells. We found that the insulin-like growth factor 1 receptor (IGF1R) gene is a target of five microRNAs whose expression is increased in LNCaP cells and reduced in DU-145 cells.Entities:
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Year: 2018 PMID： 29779108 DOI： 10.1134/S1607672918020138
Source DB: PubMed Journal: Dokl Biochem Biophys ISSN： 1607-6729 Impact factor: 0.788