| Literature DB >> 29778529 |
Pedro Madrigal1, Kaur Alasoo2.
Abstract
Recent studies involving induced pluripotent stem cell (iPSC) reprogramming in mice and monocyte-to-macrophage differentiation in humans have revealed a role for the transcription factor (TF) activator protein 1 (AP-1) in chromatin accessibility. Enhancer selection may be determined not only by cell type-specific sets of TFs but also by broadly expressed ones like AP-1.Entities:
Keywords: AP-1; ATAC-seq; cell reprogramming; chromatin accessibility
Mesh:
Substances:
Year: 2018 PMID: 29778529 DOI: 10.1016/j.tcb.2018.04.009
Source DB: PubMed Journal: Trends Cell Biol ISSN: 0962-8924 Impact factor: 20.808