Literature DB >> 29778265

A Guide to the Economics of Hepatitis C Virus Cure in 2017.

Benjamin P Linas1, Shayla Nolen2.   

Abstract

This commentary reviews the core principals of cost-effectiveness and applies them to the rapidly evolving context of hepatitis C virus treatment in the United States. The article provides a foundation of evidence that hepatitis C virus treatment provides good economic value, even though it is expensive, and even when treating people who inject drugs who are at high risk for hepatitis C virus reinfection. The price of medications has decreased, but the high price continues to limit access to care. This wedge between cost effectiveness and affordability stands front and center as one of the leading obstacles to elimination.
Copyright © 2018 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Cost-effectiveness; Health care economics; Hepatitis C Virus

Mesh:

Substances:

Year:  2018        PMID: 29778265      PMCID: PMC6085105          DOI: 10.1016/j.idc.2018.02.013

Source DB:  PubMed          Journal:  Infect Dis Clin North Am        ISSN: 0891-5520            Impact factor:   5.982


  51 in total

1.  Preference-Based EQ-5D index scores for chronic conditions in the United States.

Authors:  Patrick W Sullivan; Vahram Ghushchyan
Journal:  Med Decis Making       Date:  2006 Jul-Aug       Impact factor: 2.583

2.  Cost-Effectiveness Analysis 2.0.

Authors:  Peter J Neumann; Gillian D Sanders
Journal:  N Engl J Med       Date:  2017-01-19       Impact factor: 91.245

3.  Direct economic burden of chronic hepatitis C virus in a United States managed care population.

Authors:  Keith L Davis; Debanjali Mitra; Jasmina Medjedovic; Cynthia Beam; Vinod Rustgi
Journal:  J Clin Gastroenterol       Date:  2011-02       Impact factor: 3.062

4.  Cost-effectiveness and budget impact of hepatitis C virus treatment with sofosbuvir and ledipasvir in the United States.

Authors:  Jagpreet Chhatwal; Fasiha Kanwal; Mark S Roberts; Michael A Dunn
Journal:  Ann Intern Med       Date:  2015-03-17       Impact factor: 25.391

Review 5.  Estimation of stage-specific fibrosis progression rates in chronic hepatitis C virus infection: a meta-analysis and meta-regression.

Authors:  Hla-Hla Thein; Qilong Yi; Gregory J Dore; Murray D Krahn
Journal:  Hepatology       Date:  2008-08       Impact factor: 17.425

6.  Acute hepatitis C virus infection in young adult injection drug users: a prospective study of incident infection, resolution, and reinfection.

Authors:  Kimberly Page; Judith A Hahn; Jennifer Evans; Stephen Shiboski; Paula Lum; Eric Delwart; Leslie Tobler; William Andrews; Lia Avanesyan; Stewart Cooper; Michael P Busch
Journal:  J Infect Dis       Date:  2009-10-15       Impact factor: 5.226

7.  Research priorities to achieve universal access to hepatitis C prevention, management and direct-acting antiviral treatment among people who inject drugs.

Authors:  Jason Grebely; Julie Bruneau; Jeffrey V Lazarus; Olav Dalgard; Philip Bruggmann; Carla Treloar; Matthew Hickman; Margaret Hellard; Teri Roberts; Levinia Crooks; Håvard Midgard; Sarah Larney; Louisa Degenhardt; Hannu Alho; Jude Byrne; John F Dillon; Jordan J Feld; Graham Foster; David Goldberg; Andrew R Lloyd; Jens Reimer; Geert Robaeys; Marta Torrens; Nat Wright; Icro Maremmani; Brianna L Norton; Alain H Litwin; Gregory J Dore
Journal:  Int J Drug Policy       Date:  2017-07-03

8.  Sofosbuvir-based Regimens with Task Shifting Is Cost-effective in Expanding Hepatitis C Treatment Access in the United States.

Authors:  Channa R Jayasekera; Rachel Beckerman; Nathaniel Smith; Ryan B Perumpail; Robert J Wong; Zobair M Younossi; Aijaz Ahmed
Journal:  J Clin Transl Hepatol       Date:  2017-02-02

9.  Cost-effectiveness of sofosbuvir-based treatments for chronic hepatitis C in the US.

Authors:  Sai Zhang; Nathaniel D Bastian; Paul M Griffin
Journal:  BMC Gastroenterol       Date:  2015-08-05       Impact factor: 3.067

10.  Cost Effectiveness and Cost Containment in the Era of Interferon-Free Therapies to Treat Hepatitis C Virus Genotype 1.

Authors:  Benjamin P Linas; Jake R Morgan; Mai T Pho; Jared A Leff; Bruce R Schackman; C Robert Horsburgh; Sabrina A Assoumou; Joshua A Salomon; Milton C Weinstein; Kenneth A Freedberg; Arthur Y Kim
Journal:  Open Forum Infect Dis       Date:  2016-12-27       Impact factor: 4.423

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  2 in total

1.  Health care utilization and costs associated with direct-acting antivirals for patients with substance use disorders and chronic hepatitis C.

Authors:  Xinyi Jiang; Scott Martin Vouri; Vakaramoko Diaby; Weihsuan Lo-Ciganic; Robert Parker; Haesuk Park
Journal:  J Manag Care Spec Pharm       Date:  2021-10

2.  A minimal monitoring approach for the treatment of hepatitis C virus infection (ACTG A5360 [MINMON]): a phase 4, open-label, single-arm trial.

Authors:  Sunil S Solomon; Sandra Wagner-Cardoso; Laura Smeaton; Leonard A Sowah; Chanelle Wimbish; Gregory Robbins; Irena Brates; Christine Scello; Annie Son; Anchalee Avihingsanon; Benjamin Linas; Donald Anthony; Estevão Portela Nunes; Dimas A Kliemann; Khuanchai Supparatpinyo; Cissy Kityo; Pablo Tebas; Jaclyn Ann Bennet; Jorge Santana-Bagur; Constance A Benson; Marije Van Schalkwyk; Nelson Cheinquer; Susanna Naggie; David Wyles; Mark Sulkowski
Journal:  Lancet Gastroenterol Hepatol       Date:  2022-01-10
  2 in total

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