Merrick Miles1, Bret D Alvis2, Kyle Hocking3, Franz Baudenbacher4, Christy Guth3, Joann Lindenfeld5, Colleen Brophy3, Susan Eagle6. 1. Vanderbilt University Medical Center, Department of Anesthesiology, Division of Critical Care, Nashville, Tennessee. 2. Vanderbilt University Medical Center, Department of Anesthesiology, Division of Critical Care, Nashville, Tennessee. Electronic address: bret.d.alvis@vanderbilt.edu. 3. Vanderbilt University Medical Center, Department of Surgery, Nashville, Tennessee. 4. Vanderbilt University, Institute for Integrative Biosystems Research and Education (VIIBRE) Department of Engineering, Nashville, Tennessee. 5. Vanderbilt University Medical Center, Department of Medicine, Division of Cardiology, Nashville, Tennessee. 6. Vanderbilt University Medical Center, Department of Anesthesiology, Division of Cardiac & Thoracic Anesthesia, Nashville, Tennessee.
Abstract
BACKGROUND: To determine the feasibility of peripheral intravenous volume analysis (PIVA) of venous waveforms for assessing volume overload in patients admitted to the hospital with acute decompensated heart failure (ADHF). METHODS: Venous waveforms were captured from a peripheral intravenous catheter in subjects admitted for ADHF and healthy age-matched controls. Admission PIVA signal, brain natriuretic peptide, and chest radiographic measurements were related to the net volume removed during diuresis. RESULTS: ADHF patients had a significantly greater PIVA signal on admission compared with the control group (P = .0013, n = 18). At discharge, ADHF patients had a PIVA signal similar to the control group. PIVA signal, not brain natriuretic peptide or chest radiographic measures, accurately predicted the amount of volume removed during diuresis (R2 = 0.781, n = 14). PIVA signal at time of discharge greater than 0.20, demonstrated 83.3% 120-day readmission rate. CONCLUSIONS: This study demonstrates the feasibility of PIVA for assessment of volume overload in patients admitted to the hospital with ADHF.
BACKGROUND: To determine the feasibility of peripheral intravenous volume analysis (PIVA) of venous waveforms for assessing volume overload in patients admitted to the hospital with acute decompensated heart failure (ADHF). METHODS: Venous waveforms were captured from a peripheral intravenous catheter in subjects admitted for ADHF and healthy age-matched controls. Admission PIVA signal, brain natriuretic peptide, and chest radiographic measurements were related to the net volume removed during diuresis. RESULTS: ADHF patients had a significantly greater PIVA signal on admission compared with the control group (P = .0013, n = 18). At discharge, ADHF patients had a PIVA signal similar to the control group. PIVA signal, not brain natriuretic peptide or chest radiographic measures, accurately predicted the amount of volume removed during diuresis (R2 = 0.781, n = 14). PIVA signal at time of discharge greater than 0.20, demonstrated 83.3% 120-day readmission rate. CONCLUSIONS: This study demonstrates the feasibility of PIVA for assessment of volume overload in patients admitted to the hospital with ADHF.
Authors: Lauren D Crimmins-Pierce; Gabriel P Bonvillain; Kaylee R Henry; Md Abul Hayat; Adria Abella Villafranca; Sam E Stephens; Hanna K Jensen; Joseph A Sanford; Jingxian Wu; Kevin W Sexton; Morten O Jensen Journal: Cardiovasc Eng Technol Date: 2022-05-11 Impact factor: 2.495