Literature DB >> 29776685

Are There Pharmacotherapeutic Options for Underactive Bladder?

Nadir I Osman1, Christopher R Chapple2.   

Abstract

Currently, underactive bladder, the symptom-based correlate of the urodynamic diagnosis of detrusor underactivity, has no effective drug treatments. Use of sympathomimetics, targeting cholinergic receptors, is not supported by current evidence. Several potential targets are the subject of ongoing investigation.
Copyright © 2018 European Association of Urology. Published by Elsevier B.V. All rights reserved.

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Year:  2018        PMID： 29776685     DOI： 10.1016/j.euf.2018.03.012

Source DB:  PubMed          Journal:  Eur Urol Focus        ISSN： 2405-4569


  5 in total

1.  Prolonged nonobstructive urinary retention induced by tibial nerve stimulation in cats.

Authors:  Shun Li; Jeffery Browning; Katherine Theisen; Todd Yecies; Bing Shen; Jicheng Wang; James R Roppolo; William C de Groat; Changfeng Tai
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2020-01-08       Impact factor: 3.619

Review 2.  Potential role of oxidative stress in the pathogenesis of diabetic bladder dysfunction.

Authors:  Qi-Xiang Song; Yi Sun; Kangli Deng; Jin-Yi Mei; Christopher J Chermansky; Margot S Damaser
Journal:  Nat Rev Urol       Date:  2022-08-16       Impact factor: 16.430

3.  NF-κB and GATA-Binding Factor 6 Repress Transcription of Caveolins in Bladder Smooth Muscle Hypertrophy.

Authors:  Chellappagounder Thangavel; Cristiano M Gomes; Stephen A Zderic; Elham Javed; Sankar Addya; Jagmohan Singh; Sreya Das; Ruth Birbe; Robert B Den; Satish Rattan; Deepak A Deshpande; Raymond B Penn; Samuel Chacko; Ettickan Boopathi
Journal:  Am J Pathol       Date:  2019-01-30       Impact factor: 4.307

4.  Increased expression of desmin and vimentin reduces bladder smooth muscle contractility via JNK2.

Authors:  Elham Javed; Chellappagounder Thangavel; Nagat Frara; Jagmohan Singh; Ipsita Mohanty; Joseph Hypolite; Ruth Birbe; Alan S Braverman; Robert B Den; Satish Rattan; Stephen A Zderic; Deepak A Deshpande; Raymond B Penn; Michael R Ruggieri; Samuel Chacko; Ettickan Boopathi
Journal:  FASEB J       Date:  2019-12-16       Impact factor: 5.191

5.  Irreversible Bladder Remodeling Induced by Fibrosis.

Authors:  Su Jin Kim; Jayoung Kim; Yong Gil Na; Khae Hawn Kim
Journal:  Int Neurourol J       Date:  2021-05-31       Impact factor: 3.038
  5 in total

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