Literature DB >> 29776279

Growth of molecular diagnostics and genetic testing in the USA, 2008-2011: analysis and implications.

Jeanne De Sa1, Brantley Carlson1, Nadine Caputo2, Deneen Vojta1, Lewis Sandy1, Simon Stevens1.   

Abstract

AIMS: Advances in genomics and molecular diagnostic testing are expanding, but national data on which to base clinical, regulatory and reimbursement policies in the USA are lacking. The study objective is to provide current estimates of utilization/spending trends for private and public payers. PATIENTS &
METHODS: Healthcare utilization/expenditure claims data for 32 million individuals across the USA in 2008-2011 were analyzed. Genetic testing and molecular diagnostic usage was categorized by major testing groups: infectious disease, cancer and inherited/other acquired conditions.
RESULTS: Per-person testing cost grew by 14% per year between 2008 and 2011, primarily resulting from increased utilization. Spending per person for Medicare and Medicaid was higher than for commercially insured patients. Expenditure across the USA was estimated at US$5.5 billion in 2011, up 13% from 2010. DISCUSSION: Greater understanding of usage and technology diffusion requires increased data transparency and granularity. Conclusion & future perspective: The use of genetic testing and molecular diagnostics will grow over the next 5 years, with uncertainty about the precise diffusion trajectory. By strengthening the capacity to capture and analyze trends in this changing area of medicine, we increase our chances of promoting positive change to the benefit of patients.

Entities:  

Keywords:  genetic testing; genomics; insurance; molecular diagnostics; payment; trends; utilization

Year:  2013        PMID: 29776279     DOI: 10.2217/pme.13.84

Source DB:  PubMed          Journal:  Per Med        ISSN: 1741-0541            Impact factor:   2.512


  4 in total

1.  Genetic Test Availability And Spending: Where Are We Now? Where Are We Going?

Authors:  Kathryn A Phillips; Patricia A Deverka; Gillian W Hooker; Michael P Douglas
Journal:  Health Aff (Millwood)       Date:  2018-05       Impact factor: 6.301

Review 2.  The composition and capacity of the clinical genetics workforce in high-income countries: a scoping review.

Authors:  Nick Dragojlovic; Kennedy Borle; Nicola Kopac; Ursula Ellis; Patricia Birch; Shelin Adam; Jan M Friedman; Amy Nisselle; Alison M Elliott; Larry D Lynd
Journal:  Genet Med       Date:  2020-06-24       Impact factor: 8.822

3.  Rates of genetic testing in patients prescribed drugs with pharmacogenomic information in FDA-approved labeling.

Authors:  John Young; Kaustuv Bhattacharya; Sujith Ramachandran; Aaron Lee; John P Bentley
Journal:  Pharmacogenomics J       Date:  2021-02-15       Impact factor: 3.550

4.  Reflex test reminders in required cancer synoptic templates decrease order entry error: An analysis of mismatch repair immunohistochemical orders to screen for Lynch syndrome.

Authors:  Mark R Kilgore; Carrie A McIlwain; Rodney A Schmidt; Barbara M Norquist; Elizabeth M Swisher; Rochelle L Garcia; Mara H Rendi
Journal:  J Pathol Inform       Date:  2016-11-29
  4 in total

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