Y Peng 1 , X Q Li 2 , Q H Qiu 2 Show Affiliations »
Abstract
Objective:The aim of this study is to detect differentially expressed gene of allergic rhinitis (AR) based on RT² profiler PCR array. Method:The real-time PCR array containing 84 genes were used to compare inferior turbinate samples obtained from AR patients (n=8) and healthy individuals (n=8). Result:The results showed that 67 genes were down regulated and 17 genes were up regulated in AR inferior turbinate after analysis of 84 genes related to allergy and asthma. STAT6 and BCL6 were recognized as differentially expressed genes. Conclusion: The real-time PCR array can provide new insight into the pathophysiological processes involved in AR. Copyright© by the Editorial Department of Journal of Clinical Otorhinolaryngology Head and Neck Surgery.
Objective:The aim of this study is to detect differentially expressed gene of allergic rhinitis (AR) based on RT² profiler PCR array. Method:The real-time PCR array containing 84 genes were used to compare inferior turbinate samples obtained from AR patients (n=8) and healthy individuals (n=8). Result:The results showed that 67 genes were down regulated and 17 genes were up regulated in AR inferior turbinate after analysis of 84 genes related to allergy and asthma . STAT6 and BCL6 were recognized as differentially expressed genes. Conclusion: The real-time PCR array can provide new insight into the pathophysiological processes involved in AR. Copyright© by the Editorial Department of Journal of Clinical Otorhinolaryngology Head and Neck Surgery.
Entities: Disease
Gene
Species
Keywords:
real-time PCR array; rhinitis, allergic
Mesh： See more »
Year: 2017
PMID： 29775004 DOI： 10.13201/j.issn.1001-1781.2017.11.012
Source DB: PubMed Journal: Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi ISSN： 2096-7993