Literature DB >> 29774372

[Optical coherence tomography for skin pathologies].

J Welzel1, S Schuh2.   

Abstract

Optical coherence tomography (OCT) has become established in routine diagnosis in dermatology only in the last few years. The reason is that the skin is a challenge for OCT as a strong scattering medium, because only a very small proportion of photons is reflected and can be used for imaging. In addition, in most cases a visual assessment or a biopsy is sufficient. Nevertheless, the main field of application in dermatology is the diagnostics of epithelial skin tumors. The OCT is suitable for the early recognition of small, clinically and light microscopically unspecific basal cell carcinomas as well as for the differential diagnosis of other tumors and precancerous lesions. Using OCT, the preoperative measurement of tumor spread, observation of the course and treatment control of non-surgical procedures are possible; therefore, in many cases a biopsy or treatment control can be avoided. Dynamic OCT is a newly developed add on technique to visualize and quantify the superficial blood vessels of the skin. First studies are focused on the evaluation of tumor vessels, wound healing and monitoring of laser therapy. In ophthalmology, OCT diagnostics of basal cell carcinomas on the eyelids as well as for planning and control of eyelid interventions can be of interest.

Entities:  

Keywords:  Basal cell carcinoma; Epithelial neoplasms; Eyelid neoplasms; Non-invasive diagnostics; Therapy control

Mesh:

Year:  2018        PMID: 29774372     DOI: 10.1007/s00347-018-0718-9

Source DB:  PubMed          Journal:  Ophthalmologe        ISSN: 0941-293X            Impact factor:   1.059


  10 in total

1.  Optical coherence tomography in contact dermatitis and psoriasis.

Authors:  Julia Welzel; Maike Bruhns; Helmut H Wolff
Journal:  Arch Dermatol Res       Date:  2003-04-02       Impact factor: 3.017

2.  UVA1 and UVB irradiated skin investigated by optical coherence tomography in vivo: a preliminary study.

Authors:  T Gambichler; B Künzlberger; V Paech; A Kreuter; S Boms; A Bader; G Moussa; M Sand; P Altmeyer; K Hoffmann
Journal:  Clin Exp Dermatol       Date:  2005-01       Impact factor: 3.470

3.  Confocal laser scanning microscopy and optical coherence tomography for the evaluation of the kinetics and quantification of wound healing after fractional laser therapy.

Authors:  Elke Christina Erika Sattler; Katharina Poloczek; Raphaela Kästle; Julia Welzel
Journal:  J Am Acad Dermatol       Date:  2013-06-19       Impact factor: 11.527

4.  Optical coherence tomography of the human skin.

Authors:  J Welzel; E Lankenau; R Birngruber; R Engelhardt
Journal:  J Am Acad Dermatol       Date:  1997-12       Impact factor: 11.527

Review 5.  Dynamic Optical Coherence Tomography in Dermatology.

Authors:  Martina Ulrich; Lotte Themstrup; Nathalie de Carvalho; Marco Manfredi; Costantino Grana; Silvana Ciardo; Raphaela Kästle; Jon Holmes; Richard Whitehead; Gregor B E Jemec; Giovanni Pellacani; Julia Welzel
Journal:  Dermatology       Date:  2016-04-23       Impact factor: 5.366

6.  The sensitivity and specificity of optical coherence tomography for the assisted diagnosis of nonpigmented basal cell carcinoma: an observational study.

Authors:  M Ulrich; T von Braunmuehl; H Kurzen; T Dirschka; C Kellner; E Sattler; C Berking; J Welzel; U Reinhold
Journal:  Br J Dermatol       Date:  2015-07-20       Impact factor: 9.302

7.  In vivo microvascular imaging of cutaneous actinic keratosis, Bowen's disease and squamous cell carcinoma using dynamic optical coherence tomography.

Authors:  L Themstrup; G Pellacani; J Welzel; J Holmes; G B E Jemec; M Ulrich
Journal:  J Eur Acad Dermatol Venereol       Date:  2017-06-20       Impact factor: 6.166

8.  Optical coherence tomography of actinic keratoses and basal cell carcinomas - differentiation by quantification of signal intensity and layer thickness.

Authors:  S Schuh; R Kaestle; E C Sattler; J Welzel
Journal:  J Eur Acad Dermatol Venereol       Date:  2016-02-24       Impact factor: 6.166

9.  Optical coherence tomography for margin definition of basal cell carcinoma before micrographic surgery-recommendations regarding the marking and scanning technique.

Authors:  N De Carvalho; S Schuh; N Kindermann; R Kästle; J Holmes; J Welzel
Journal:  Skin Res Technol       Date:  2017-10-23       Impact factor: 2.365

10.  Optical coherence tomography for the diagnosis of malignant skin tumors: a meta-analysis.

Authors:  Yi-Quan Xiong; Yun Mo; Yu-Qi Wen; Ming-Ji Cheng; Shu-Ting Huo; Xue-Jiao Chen; Qing Chen
Journal:  J Biomed Opt       Date:  2018-02       Impact factor: 3.170

  10 in total

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