Y A Li1, I Martin2, R Tsang2, S G Squires1, W Demczuk2, S Desai1. 1. Infectious Disease Prevention and Control Branch, Public Health Agency of Canada Ottawa, ON. 2. National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MN.
Abstract
BACKGROUND: Northern populations were at a high risk of developing invasive bacterial diseases (IBDs). Since the last published study that described IBDs in Northern Canada, a number of vaccines against some bacterial pathogens have been introduced into the routine childhood immunization schedule. OBJECTIVE: To describe the epidemiology of IBDs in Northern Canada from 2006 to 2013. METHODS: Data for 5 IBDs (invasive pneumococcal disease (IPD), invasive Haemophilus influenzae disease (Hi), invasive Group A streptococcal disease (iGAS), invasive meningococcal disease (IMD) and invasive Group B streptococcal disease (GBS)) were extracted from the International Circumpolar Surveillance (ICS) program and the Canadian Notifiable Diseases Surveillance System. Incidence rates were calculated per 100,000 population per year. RESULTS: During the study period, the incidence rates of IPD ranged from 16.84-30.97, iGAS 2.70-17.06, Hi serotype b 0-2.78, Hi non-b type 2.73-8.53, and IMD 0-3.47. Except for IMD and GBS, the age-standardized incidence rates of other diseases in Northern Canada were 2.6-10 times higher than in the rest of Canada. Over the study period, rates decreased for IPD (p=0.04), and iGAS (p=0.01), and increased for Hi type a (Hia) (p=0.004). Among IPD cases, the proportion of pneumococcal conjugate vaccine (PCV)7 serotypes decreased (p=0.0004) over the study period. Among Hi cases, 69.8% were Hia and 71.6% of these were in children under than 5 years. Of 13 IMD cases, 8 were serogroup B and 2 of them died. CONCLUSION: Northern population in Canada, especially infants and seniors among First Nations and Inuit, are at a high risk of IPD, Hi and iGAS. Hia is the predominant serotype in Northern Canada.
BACKGROUND: Northern populations were at a high risk of developing invasive bacterial diseases (IBDs). Since the last published study that described IBDs in Northern Canada, a number of vaccines against some bacterial pathogens have been introduced into the routine childhood immunization schedule. OBJECTIVE: To describe the epidemiology of IBDs in Northern Canada from 2006 to 2013. METHODS: Data for 5 IBDs (invasive pneumococcal disease (IPD), invasive Haemophilus influenzae disease (Hi), invasive Group A streptococcal disease (iGAS), invasive meningococcal disease (IMD) and invasive Group B streptococcal disease (GBS)) were extracted from the International Circumpolar Surveillance (ICS) program and the Canadian Notifiable Diseases Surveillance System. Incidence rates were calculated per 100,000 population per year. RESULTS: During the study period, the incidence rates of IPD ranged from 16.84-30.97, iGAS 2.70-17.06, Hi serotype b 0-2.78, Hi non-b type 2.73-8.53, and IMD 0-3.47. Except for IMD and GBS, the age-standardized incidence rates of other diseases in Northern Canada were 2.6-10 times higher than in the rest of Canada. Over the study period, rates decreased for IPD (p=0.04), and iGAS (p=0.01), and increased for Hi type a (Hia) (p=0.004). Among IPD cases, the proportion of pneumococcal conjugate vaccine (PCV)7 serotypes decreased (p=0.0004) over the study period. Among Hi cases, 69.8% were Hia and 71.6% of these were in children under than 5 years. Of 13 IMD cases, 8 were serogroup B and 2 of them died. CONCLUSION: Northern population in Canada, especially infants and seniors among First Nations and Inuit, are at a high risk of IPD, Hi and iGAS. Hia is the predominant serotype in Northern Canada.
Authors: Anna Banerji; David Greenberg; Laura Forsberg White; W Alexander Macdonald; Audrey Saxton; Eva Thomas; Douglas Sage; Muhammad Mamdani; Krista L Lanctôt; James B Mahony; Mia Dingle; Ann Roberts Journal: Pediatr Infect Dis J Date: 2009-08 Impact factor: 2.129
Authors: Rosalyn Singleton; Laura Hammitt; Thomas Hennessy; Lisa Bulkow; Carolynn DeByle; Alan Parkinson; Tammy E Cottle; Helen Peters; Jay C Butler Journal: Pediatrics Date: 2006-08 Impact factor: 7.124
Authors: Grace Huang; Irene Martin; Raymond S Tsang; Walter H Demczuk; Gregory J Tyrrell; Y Anita Li; Catherine Dickson; Francesca Reyes-Domingo; Susan G Squires Journal: Can Commun Dis Rep Date: 2021-11-10