Literature DB >> 2976997

The production of tumor necrosis factor-alpha by rat basophilic leukemia cells with triggering IgE receptor.

I Ohno1, Y Tanno, K Yamauchi, S Ida, T Takishima.   

Abstract

We evaluated cytotoxic factor released from rat basophilic leukemia cells (RBL) sensitized with anti-ovalbumin (OVA) mouse serum after incubation with OVA. The cytotoxic activity of this factor was completely blocked by anti-mouse tumor necrosis factor-alpha (mTNF-alpha) specific antibody. Therefore, we concluded that by triggering the IgE receptor, RBL could produce and release TNF-alpha.

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Year:  1988        PMID： 2976997     DOI： 10.1620/tjem.156.209

Source DB:  PubMed          Journal:  Tohoku J Exp Med        ISSN： 0040-8727            Impact factor:   1.848


  2 in total

1.  Production of tumour necrosis factor by mastocytoma P815 cells.

Authors:  I Ohno; Y Tanno; K Yamauchi; T Takishima
Journal:  Immunology       Date:  1990-02       Impact factor: 7.397

2.  Gene expression and production of tumour necrosis factor by a rat basophilic leukaemia cell line (RBL-2H3) with IgE receptor triggering.

Authors:  I Ohno; Y Tanno; K Yamauchi; T Takishima
Journal:  Immunology       Date:  1990-05       Impact factor: 7.397
  2 in total

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