A Boggild1, J Brophy2, P Charlebois3, M Crockett4, J Geduld5, W Ghesquiere6, P McDonald7, P Plourde8, P Teitelbaum9, M Tepper10, S Schofield11, A McCarthy12. 1. University Health Network, Toronto General Hospital, Toronto, Ontario. 2. Division of Infectious Diseases, Children's Hospital of Eastern Ontario, Ottawa, Ontario. 3. Internal Medicine, Canadian Forces Health Services Centre (Atlantic), Halifax, Nova Scotia. 4. Paediatrics and Child Health, University of Manitoba, Winnipeg, Manitoba. 5. Infectious Disease Prevention and Control Branch, Public Health Agency of Canada, Ottawa, Ontario. 6. Infectious Diseases and Internal Medicine, University of British Columbia, Victoria, British Columbia. 7. Therapeutic Products Directorate, Health Canada, Ottawa, Ontario. 8. Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba. 9. Riverside Travel Medicine Clinic, Ottawa, Ontario. 10. Communicable Disease Control Program, Directorate of Force Health Protection (Ottawa, Ontario). 11. Pest Management Entomology, Directorate of Force Health Protection, Ottawa, Ontario. 12. Tropical Medicine and International Health Clinic, Division of Infectious Disease, Ottawa Hospital General Campus, Ottawa, Ontario.
Abstract
BACKGROUND: On behalf of the Public Health Agency of Canada, the Committee to Advise on Tropical Medicine and Travel (CATMAT) developed the Canadian Recommendations for the Prevention and Treatment of Malaria Among International Travellers for Canadian health care providers who are preparing patients for travel to malaria-endemic areas and treating travellers who have returned ill. OBJECTIVE: To provide guidelines on malaria issues related to special hosts. METHODS: CATMAT reviewed all major sources of information on malaria prevention, as well as recent research and national and international epidemiological data, to tailor guidelines to the Canadian context. The evidence-based medicine recommendations were developed with associated rating scales for the strength and quality of the evidence. RECOMMENDATIONS: All people visiting malaria endemic regions should use effective personal protective measures (PPM; topical repellants, bed nets, behavioural choices) and the prescribed chemoprophylaxis. Chemoprophylaxis for pregnant and breastfeeding women and for children requires careful consideration in the context of the pregnancy trimester, the age or size of the infant/child as well as their glucose-6-phosphate dehydrogenase (G6PD) status. Recommendations for long-term travellers, expatriates and people visiting friends and relatives (VFRs) do not differ markedly from those for short-term travellers. Some underlying medical conditions may make individuals more vulnerable to malaria. In addition, some conditions or their treatment may preclude the use of one or more antimalarial medications.
BACKGROUND: On behalf of the Public Health Agency of Canada, the Committee to Advise on Tropical Medicine and Travel (CATMAT) developed the Canadian Recommendations for the Prevention and Treatment of Malaria Among International Travellers for Canadian health care providers who are preparing patients for travel to malaria-endemic areas and treating travellers who have returned ill. OBJECTIVE: To provide guidelines on malaria issues related to special hosts. METHODS: CATMAT reviewed all major sources of information on malaria prevention, as well as recent research and national and international epidemiological data, to tailor guidelines to the Canadian context. The evidence-based medicine recommendations were developed with associated rating scales for the strength and quality of the evidence. RECOMMENDATIONS: All people visiting malaria endemic regions should use effective personal protective measures (PPM; topical repellants, bed nets, behavioural choices) and the prescribed chemoprophylaxis. Chemoprophylaxis for pregnant and breastfeeding women and for children requires careful consideration in the context of the pregnancy trimester, the age or size of the infant/child as well as their glucose-6-phosphate dehydrogenase (G6PD) status. Recommendations for long-term travellers, expatriates and people visiting friends and relatives (VFRs) do not differ markedly from those for short-term travellers. Some underlying medical conditions may make individuals more vulnerable to malaria. In addition, some conditions or their treatment may preclude the use of one or more antimalarial medications.
Authors: P Newton; S Proux; M Green; F Smithuis; J Rozendaal; S Prakongpan; K Chotivanich; M Mayxay; S Looareesuwan; J Farrar; F Nosten; N J White Journal: Lancet Date: 2001-06-16 Impact factor: 79.321
Authors: J E Touze; P Heno; L Fourcade; J C Deharo; G Thomas; S Bohan; P Paule; P Riviere; E Kouassi; A Buguet Journal: Am J Trop Med Hyg Date: 2002-07 Impact factor: 2.345
Authors: Robert Cockburn; Paul N Newton; E Kyeremateng Agyarko; Dora Akunyili; Nicholas J White Journal: PLoS Med Date: 2005-03-14 Impact factor: 11.069