Literature DB >> 29768561

The role of the Xpert MTB/RIF assay among adolescents suspected of pulmonary tuberculosis in Rio de Janeiro, Brazil.

Thania Luiza de Andrade Sieiro1, Rafaela Baroni Aurílio2, Elizabeth Cristina C Soares3, Silvia S Chiang4, Clemax Couto Sant Anna5,6.   

Abstract

INTRODUCTION: The teste rápido molecular para tuberculose (TRM-TB) was introduced in 2014 in Brazil for tuberculosis screening. However, its role in adolescents in Brazil has not been studied.
METHODS: A descriptive study of adolescents with suspected tuberculosis using National Laboratory software.
RESULTS: Of 852 (15.4%) suspected cases, 131 were positive by TRM-TB and 2% were resistant to rifampicin. Among TRM-TB-positive cases, 105 (91.4%) were culture-positive. Sixty-four of 96 samples were sensitive to rifampicin by TRM-TB; 11 were resistant to other drugs by drug sensitivity test (DST).
CONCLUSIONS: Among suspected cases, 16% were diagnosed by TRM-TB, of which 17% were drug-resistant by DST.

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Year:  2018        PMID: 29768561     DOI: 10.1590/0037-8682-0298-2017

Source DB:  PubMed          Journal:  Rev Soc Bras Med Trop        ISSN: 0037-8682            Impact factor:   1.581


  5 in total

1.  Differences in CT imaging signs between patients with tuberculosis and those with tuberculosis and concurrent lung cancer.

Authors:  Wencai Tang; Weijin Xing; Chuanzi Li; Zhongshi Nie; Mubin Cai
Journal:  Am J Transl Res       Date:  2022-09-15       Impact factor: 3.940

Review 2.  Xpert MTB/RIF Ultra assay for tuberculosis disease and rifampicin resistance in children.

Authors:  Alexander W Kay; Tara Ness; Sabine E Verkuijl; Kerri Viney; Annemieke Brands; Tiziana Masini; Lucia González Fernández; Michael Eisenhut; Anne K Detjen; Anna M Mandalakas; Karen R Steingart; Yemisi Takwoingi
Journal:  Cochrane Database Syst Rev       Date:  2022-09-06

Review 3.  Epidemiological aspects, clinical manifestations, and prevention of pediatric tuberculosis from the perspective of the End TB Strategy.

Authors:  Anna Cristina Calçada Carvalho; Claudete Aparecida Araújo Cardoso; Terezinha Miceli Martire; Giovanni Battista Migliori; Clemax Couto Sant'Anna
Journal:  J Bras Pneumol       Date:  2018-04       Impact factor: 2.624

4.  Xpert MTB/RIF performance to diagnose tuberculosis and rifampicin resistance in a reference centre in southern Brazil.

Authors:  Cinara Silva Feliciano; Lucas José Bazzo Menon; Livia Maria Pala Anselmo; Anzaan Dippenaar; Robin Mark Warren; Wilson Araújo Silva; Valdes Roberto Bollela
Journal:  ERJ Open Res       Date:  2019-08-05

5.  Xpert MTB/RIF and Xpert MTB/RIF Ultra assays for active tuberculosis and rifampicin resistance in children.

Authors:  Alexander W Kay; Lucia González Fernández; Yemisi Takwoingi; Michael Eisenhut; Anne K Detjen; Karen R Steingart; Anna M Mandalakas
Journal:  Cochrane Database Syst Rev       Date:  2020-08-27
  5 in total

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