Massive bilateral retinal vascular occlusion secondary to thrombotic thrombocytopenic purpura.

An 18-year-old woman developed sudden diffuse bilateral retinal vascular occlusive disease secondary to thrombotic thrombocytopenic purpura. This microangiopathic disease resulted in massive bilateral capillary closure and severe visual loss. Visual loss occurred while responding to therapy for this immune-mediated disease. This report is the first description of extensive retinal vascular occlusion in thrombotic thrombocytopenic purpura.