Literature DB >> 29764786

Instability in Patients with CANVAS: Can Computerized Dynamic Posturography Help in Diagnosis?

Alba Marina Milá de la Roca-Morales1, Joan F Andreo-Marroig2, Sofía Santos-Pérez3, Andrés Soto-Varela3.   

Abstract

OBJECTIVE: To describe the pattern of dynamic posturography or its role in diagnosis in patients with cerebellar ataxia with neuropathy and vestibular arreflexia syndrome (CANVAS).
MATERIALS AND METHODS: We present and describe posturographic data of four patients diagnosed with the CANVAS syndrome in a tertiary hospital.
RESULTS: In all patients, the average balance score was diminished. Two patients presented a pattern of visual dependence. The other two showed misuse of three posturography sensory information (visual, vestibular and propioceptive information), specially null use of vestibular information, deterioration of somatosensory input, and poor use of strategies, particularly in conditions 5 and 6.
CONCLUSIONS: If there is misuse of somatosensory information in sensory organization test (SOT) in a patient with bilateral vestibular deficit, a possibility of CANVAS should be considered. The SOT provides valuable information, because it evaluates sensory inputs influence the maintenance of balance.

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Mesh:

Year:  2018        PMID: 29764786      PMCID: PMC6354493          DOI: 10.5152/iao.2018.4335

Source DB:  PubMed          Journal:  J Int Adv Otol        ISSN: 1308-7649            Impact factor:   1.017


  7 in total

Review 1.  Cerebellar ataxia, neuropathy, vestibular areflexia syndrome (CANVAS): a review of the clinical features and video-oculographic diagnosis.

Authors:  David J Szmulewicz; John A Waterston; Hamish G MacDougall; Stuart Mossman; Andrew M Chancellor; Catriona A McLean; Saumil Merchant; Peter Patrikios; G Michael Halmagyi; Elsdon Storey
Journal:  Ann N Y Acad Sci       Date:  2011-09       Impact factor: 5.691

Review 2.  Proposed diagnostic criteria for cerebellar ataxia with neuropathy and vestibular areflexia syndrome (CANVAS).

Authors:  David J Szmulewicz; Leslie Roberts; Catriona A McLean; Hamish G MacDougall; G Michael Halmagyi; Elsdon Storey
Journal:  Neurol Clin Pract       Date:  2016-02

3.  Syndrome of cerebellar ataxia, neuropathy and vestibular areflexia: diagnosis by caloric vestibular stimulation.

Authors:  José Antonio Crespo-Burillo; Natalia Hernando Quintana; Jesús Fraile Rodrigo; José Gazulla
Journal:  Neurologia       Date:  2012-08-11       Impact factor: 3.109

4.  [Cerebellar ataxia with neuropathy and bilateral vestibular areflexia syndrome (CANVAS) in an imbalance patient].

Authors:  Jesús J Benítez del Rosario; María Elvira Santandreu Jiménez; Manuel Lousa Gayoso
Journal:  Acta Otorrinolaringol Esp       Date:  2013-04-12

5.  Sensory neuropathy as part of the cerebellar ataxia neuropathy vestibular areflexia syndrome.

Authors:  D J Szmulewicz; J A Waterston; G M Halmagyi; S Mossman; A M Chancellor; C A McLean; E Storey
Journal:  Neurology       Date:  2011-05-31       Impact factor: 9.910

6.  Cerebellar ataxia with bilateral vestibulopathy: description of a syndrome and its characteristic clinical sign.

Authors:  Americo A Migliaccio; G Michael Halmagyi; Leigh A McGarvie; Phillip D Cremer
Journal:  Brain       Date:  2003-11-07       Impact factor: 13.501

7.  Autonomic dysfunction is a major feature of cerebellar ataxia, neuropathy, vestibular areflexia 'CANVAS' syndrome.

Authors:  Teddy Y Wu; Jennifer M Taylor; Dean H Kilfoyle; Andrew D Smith; Ben J McGuinness; Mark P Simpson; Elizabeth B Walker; Peter S Bergin; James C Cleland; David O Hutchinson; Neil E Anderson; Barry J Snow; Tim J Anderson; Laura A F Paermentier; Nick J Cutfield; Andrew M Chancellor; Stuart S Mossman; Richard H Roxburgh
Journal:  Brain       Date:  2014-07-28       Impact factor: 13.501

  7 in total

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