Literature DB >> 29763935

Comorbidities Are Associated with Altered Health Services Use in Multiple Sclerosis: A Prospective Cohort Study.

Kyla A McKay1, Ruth Ann Marrie2, John D Fisk3, Scott B Patten4, Helen Tremlett1.   

Abstract

BACKGROUND: Persons with multiple sclerosis (MS) use health resources with greater frequency than the general population. However, little is known regarding which patient characteristics might contribute.
OBJECTIVE: The study aimed to evaluate characteristics associated with healthcare use in MS patients.
METHODS: Consecutive MS clinic attendees were recruited (September-November 2010), with clinical, demographic, and patient-completed questionnaires collected at 3 visits over 2 years. Linkage with administrative data (hospital, physician, and pharmacy records) provided healthcare use outcomes until December 31, 2013. Findings were reported as adjusted rate ratios (adjRRs) using negative binomial regression.
RESULTS: A total of 340 MS patients with a mean (SD) age of 48.4 (12.0) years and subsequent follow-up of 3.1 (0.34) years were included. Fatigue and high physical comorbidity count (≥3 vs. none) were significantly associated with higher rates of physician encounters (adjRRs: 1.37 and 1.52, respectively), prescriptions filled (adjRRs: 1.25 and 1.40), and hospitalizations (adjRRs: 4.02 and 3.45). In addition, anxiety, disruptive pain, and perceived functional cognitive difficulties were associated with higher rates of physician encounters and prescriptions dispensed (adjRR ranged from 1.28 to 1.48). DISCUSSION: The presence of fatigue and higher physical comorbidity burden were associated with higher rates of health services use. Findings have implications for those examining healthcare burden or organizing health services for persons with MS.
© 2018 S. Karger AG, Basel.

Entities:  

Keywords:  Comorbidity; Fatigue; Health services use; Multiple sclerosis

Mesh:

Year:  2018        PMID: 29763935     DOI: 10.1159/000488799

Source DB:  PubMed          Journal:  Neuroepidemiology        ISSN: 0251-5350            Impact factor:   3.282


  3 in total

Review 1.  Therapeutic Advances and Challenges in the Treatment of Progressive Multiple Sclerosis.

Authors:  Laura E Baldassari; Robert J Fox
Journal:  Drugs       Date:  2018-10       Impact factor: 11.431

2.  Prevalence and burden of multiple sclerosis-related fatigue: a systematic literature review.

Authors:  Abril Oliva Ramirez; Alexander Keenan; Olivia Kalau; Evelyn Worthington; Lucas Cohen; Sumeet Singh
Journal:  BMC Neurol       Date:  2021-12-02       Impact factor: 2.474

3.  Use of healthcare services by patients with multiple sclerosis in France over 2010-2015: a nationwide population-based study using health administrative data.

Authors:  J Roux; A Guilleux; M Lefort; E Leray
Journal:  Mult Scler J Exp Transl Clin       Date:  2019-12-18
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.