Literature DB >> 29762277

Impact of Clinical Practice Guidelines on Use of Intra-Articular Hyaluronic Acid and Corticosteroid Injections for Knee Osteoarthritis.

Nicholas A Bedard1, David E DeMik1, Natalie A Glass1, Robert A Burnett1, Kevin J Bozic2, John J Callaghan1.   

Abstract

BACKGROUND: The efficacy of corticosteroid and hyaluronic acid injections for knee osteoarthritis has been questioned. The purpose of this study was to determine the impact of the American Academy of Orthopaedic Surgeons (AAOS) clinical practice guidelines on the use of these injections in the United States and determine if utilization differed by provider specialty.
METHODS: Patients with knee osteoarthritis were identified within the Humana database from 2007 to 2015, and the percentage of patients receiving a knee injection relative to the number of patients having an encounter for knee osteoarthritis was calculated and was trended for the study period. The impact of each edition of the AAOS clinical practice guidelines on injection use was evaluated with segmented regression analysis. Injection trends were also analyzed relative to the specialty of the provider performing the injection.
RESULTS: Of 1,065,175 patients with knee osteoarthritis, 405,101 (38.0%) received a corticosteroid injection and 137,005 (12.9%) received a hyaluronic acid injection. The rate of increase in hyaluronic acid use, per 100 patients with knee osteoarthritis, decreased from 0.15 to 0.07 injection per quarter year (p = 0.02) after the first clinical practice guideline, and the increase changed to a decrease at a rate of -0.12 injection per quarter (p < 0.001) after the second clinical practice guideline. After the first clinical practice guideline, the rate of increase in utilization of corticosteroids, per 100 patients with knee osteoarthritis, significantly lessened to 0.12 injection per quarter (p < 0.001), and after the second clinical practice guideline, corticosteroid injection use plateaued (p = 0.72). The trend in use of hyaluronic acid injections by orthopaedic surgeons and pain specialists decreased with time following the second-edition clinical practice guideline but did not change for primary care physicians or nonoperative musculoskeletal providers.
CONCLUSIONS: Subtle but significant changes in hyaluronic acid and corticosteroid injections occurred following the publication of both clinical practice guidelines. Although the clinical practice guidelines did impact injection use, given the high costs of these injections and their questionable clinical efficacy, further interventions beyond publishing clinical practice guidelines are needed to encourage higher-value care for patients with knee osteoarthritis.

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Year:  2018        PMID: 29762277     DOI: 10.2106/JBJS.17.01045

Source DB:  PubMed          Journal:  J Bone Joint Surg Am        ISSN: 0021-9355            Impact factor:   5.284


  9 in total

1.  Prior Intra-articular Corticosteroid Injection Within 3 Months May Increase the Risk of Deep Infection in Subsequent Joint Arthroplasty: A Meta-analysis.

Authors:  Qizhong Lai; Kaishen Cai; Tianye Lin; Chi Zhou; Zhenqiu Chen; Qingwen Zhang
Journal:  Clin Orthop Relat Res       Date:  2021-12-17       Impact factor: 4.755

2.  Intra-Articular Injection of Platelet-Rich Plasma Is More Effective than Hyaluronic Acid or Steroid Injection in the Treatment of Mild to Moderate Knee Osteoarthritis: A Prospective, Randomized, Triple-Parallel Clinical Trial.

Authors:  Dawid Szwedowski; Ali Mobasheri; Andrzej Moniuszko; Jan Zabrzyński; Sławomir Jeka
Journal:  Biomedicines       Date:  2022-04-25

3.  Treatment and Healthcare Cost Among Patients with Hip or Knee Osteoarthritis: A Cross-sectional Study Using a Real-world Claims Database in Japan Between 2013 and 2019.

Authors:  Nozomi Ebata-Kogure; Aya Murakami; Kazutaka Nozawa; Koichi Fujii; Yingsong Lin; Takahiro Ushida; Shogo Kikuchi
Journal:  Clin Drug Investig       Date:  2020-11       Impact factor: 2.859

Review 4.  Intra-articular treatment options for knee osteoarthritis.

Authors:  Ian A Jones; Ryan Togashi; Melissa L Wilson; Nathanael Heckmann; C Thomas Vangsness
Journal:  Nat Rev Rheumatol       Date:  2019-02       Impact factor: 20.543

5.  MultiCenter Interrupted Time Series Analysis: Incorporating Within and Between-Center Heterogeneity.

Authors:  Joycelyne E Ewusie; Lehana Thabane; Joseph Beyene; Sharon E Straus; Jemila S Hamid
Journal:  Clin Epidemiol       Date:  2020-06-17       Impact factor: 4.790

6.  Impact of Knee Injuries on Post-retirement Pain and Quality of Life: A Cross-Sectional Survey of Professional Basketball Players.

Authors:  Moin Khan; Seper Ekhtiari; Tyrrell Burrus; Kim Madden; Joseph P Rogowski; Asheesh Bedi
Journal:  HSS J       Date:  2019-11-08

7.  Treatment of Unicompartmental Cartilage Defects of the Knee with Unicompartmental Knee Arthroplasty, Patellofemoral Partial Knee Arthroplasty or Focal Resurfacing.

Authors:  Bernhard Springer; Friedrich Boettner
Journal:  Life (Basel)       Date:  2021-04-27

8.  Hyaluronan Injections Show No Histologic Evidence of Adverse Tissue Effects.

Authors:  Michael Bisogno; Saman Vojdani; Marriam Aalai; Daniel Shapiro; Meghan Moriarty; Vincent Vigorita; James Capozzi
Journal:  Geriatr Orthop Surg Rehabil       Date:  2019-07-31

9.  Consequences on Private Insurance Coverage: The AAOS Clinical Practice Guidelines and Hyaluronic Acid Injections.

Authors:  C Thomas Vangsness; Thomas C Adamson; Michael J Daley
Journal:  J Bone Joint Surg Am       Date:  2020-05-20       Impact factor: 6.558

  9 in total

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