| Literature DB >> 2976092 |
B P Imbimbo1, E Imbimbo, S Daniotti, D Verotta, G Bassotti.
Abstract
In linear pharmacokinetics, the time course of the plasma concentration of a drug, Ct, is expressed by the sum of exponential terms, (formula; see text) This article proposes a new statistical criterion for discriminating between alternate polyexponential models. According to this new criterion, the model that best interprets a set of experimental data points is that which minimizes the area between the approximate confidence limits of Ct.Mesh：
Substances：
Year: 1988 PMID： 2976092 DOI： 10.1002/jps.2600770914
Source DB: PubMed Journal: J Pharm Sci ISSN： 0022-3549 Impact factor: 3.534